3-Bromo-4-methoxy-1-methylpyridin-2(1H)-one

Base Information

Chemical Name:3-Bromo-4-methoxy-1-methylpyridin-2(1H)-one
CAS No.:920490-72-8
Molecular Formula:C7H8BrNO2
Molecular Weight:218.04800
Hs Code.:
DSSTox Substance ID:DTXSID50580822
Nikkaji Number:J599.191I
Wikidata:Q82471800
Mol file:920490-72-8.mol

Synonyms:3-Bromo-4-methoxy-1-methylpyridin-2(1H)-one;920490-72-8;3-BROMO-4-METHOXY-1-METHYLPYRIDIN-2-ONE;SCHEMBL21957151;DTXSID50580822;MFCD22380500;AKOS027339272;AS-40992;CS-0325844

Suppliers and Price of 3-Bromo-4-methoxy-1-methylpyridin-2(1H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-bromo-4-methoxy-1-methylpyridin-2(1H)-one
100mg
$ 330.00

Matrix Scientific
3-Bromo-4-methoxy-1-methylpyridin-2(1H)-one
5g
$ 3000.00

Matrix Scientific
3-Bromo-4-methoxy-1-methylpyridin-2(1H)-one
1g
$ 1050.00

Crysdot
3-Bromo-4-methoxy-1-methylpyridin-2(1H)-one 97%
1g
$ 705.00

Alichem
3-Bromo-4-methoxy-1-methylpyridin-2(1h)-one
1g
$ 816.75

Total 4 raw suppliers

Chemical Property of 3-Bromo-4-methoxy-1-methylpyridin-2(1H)-one

Chemical Property:

PSA：31.23000
LogP:1.15640
XLogP3:1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:216.97384
Heavy Atom Count:11
Complexity:245

Purity/Quality:

95% ^*data from raw suppliers

3-bromo-4-methoxy-1-methylpyridin-2(1H)-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN1C=CC(=C(C1=O)Br)OC

Technology Process of 3-Bromo-4-methoxy-1-methylpyridin-2(1H)-one

There total 1 articles about 3-Bromo-4-methoxy-1-methylpyridin-2(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 41759-19-7
4-methoxy-1-methyl-2-pyridone

: 920490-72-8
3-bromo-4-methoxy-1-methylpyridin-2(1H)-one

Guidance literature:: With bromine; acetic acid; In dichloromethane; at 20 ℃; for 15h;
DOI:10.1021/ol062721u

Reference yield: 95.0%

: 920490-72-8
3-bromo-4-methoxy-1-methylpyridin-2(1H)-one

: 920490-71-7
3-bromo-5-iodo-4-methoxy-1-methylpyridin-2(1H)-one

Guidance literature:: With N-iodo-succinimide; trifluoroacetic acid; In acetonitrile; at 20 ℃; for 15h;
DOI:10.1021/ol062721u

Reference yield:

: 920490-72-8
3-bromo-4-methoxy-1-methylpyridin-2(1H)-one

: 3-bromo-4-methoxy-1-methyl-5-(4-methylphenyl)pyridin-2(1H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / N-iodosuccinimide; trifluoroacetic acid / acetonitrile / 15 h / 20 °C

2: 87 percent / tris(3-sulfonatophenyl)phosphane trisodium salt; diisopropylamine / Pd(OAc)2 / acetonitrile; H₂O / 16 h / 80 °C

With N-iodo-succinimide; trisodium tris(3-sulfophenyl)phosphine; diisopropylamine; trifluoroacetic acid; palladium diacetate; In water; acetonitrile; 2: Suzuki cross-coupling;
DOI:10.1021/ol062721u