Propanal, 3-[(4-methoxyphenyl)methoxy]-2,2-dimethyl-

Base Information

Chemical Name:Propanal, 3-[(4-methoxyphenyl)methoxy]-2,2-dimethyl-
CAS No.:92156-87-1
Molecular Formula:C13H18O3
Molecular Weight:222.284
Hs Code.:
DSSTox Substance ID:DTXSID50454695
Nikkaji Number:J695.088D
Wikidata:Q82276373

Synonyms:Propanal, 3-[(4-methoxyphenyl)methoxy]-2,2-dimethyl-;92156-87-1;SCHEMBL3799734;DTXSID50454695;LIGFTVUHBAHFJF-UHFFFAOYSA-N;2,2-Dimethyl-3-(4-methoxybenzyloxy)propanal;2,2-Dimethyl-3-(4-methoxyphenylmethoxy)propionaldehyde

Suppliers and Price of Propanal, 3-[(4-methoxyphenyl)methoxy]-2,2-dimethyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Propanal, 3-[(4-methoxyphenyl)methoxy]-2,2-dimethyl-

Chemical Property:

Boiling Point:325.9±22.0 °C(Predicted)
PSA：35.53000
Density:1.029±0.06 g/cm3(Predicted)
LogP:2.43690
XLogP3:1.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:222.125594432
Heavy Atom Count:16
Complexity:205

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(COCC1=CC=C(C=C1)OC)C=O

Technology Process of Propanal, 3-[(4-methoxyphenyl)methoxy]-2,2-dimethyl-

There total 5 articles about Propanal, 3-[(4-methoxyphenyl)methoxy]-2,2-dimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 446264-36-4
3-[(4-methoxyphenyl)methoxy]-2,2-dimethyl-propan-1-ol

: 92156-87-1
2,2-dimethyl-3-(4-methoxyphenylmethoxy)propionaldehyde

Guidance literature:: With Dess-Martin periodane; In dichloromethane; at 20 ℃; for 4h; Cooling with ice;

Reference yield:

: 2746-25-0
p-Methoxybenzyl bromide

: 92156-87-1
2,2-dimethyl-3-(4-methoxyphenylmethoxy)propionaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: NaH; Bu₄NI / tetrahydrofuran / 0 °C

2: (COCl)2; DMSO; Et₃N / CH₂Cl₂ / -78 °C

With oxalyl dichloride; tetra-(n-butyl)ammonium iodide; sodium hydride; dimethyl sulfoxide; triethylamine; In tetrahydrofuran; dichloromethane; 2: Swern oxidation;
DOI:10.1021/ol034035q