Diethyl 2-(phenylcarbamoyl)propanedioate

Base Information

Chemical Name:Diethyl 2-(phenylcarbamoyl)propanedioate
CAS No.:16798-45-1
Molecular Formula:C14H17 N O5
Molecular Weight:279.293
Hs Code.:2924299090
NSC Number:165840
DSSTox Substance ID:DTXSID80937421
Wikidata:Q82913646
Mol file:16798-45-1.mol

Synonyms:diethyl 2-(phenylcarbamoyl)propanedioate;diethyl 2-(anilinocarbonyl)malonate;NSC165840;SCHEMBL10740441;DTXSID80937421;ethyl 2-ethoxycarbonylmalonanilate;AKOS024323176;NSC-165840;FT-0624775;FT-0624879;A810927;2-[anilino(oxo)methyl]propanedioic acid diethyl ester;3-Ethoxy-2-(ethoxycarbonyl)-3-oxo-N-phenylpropanimidic acid

Suppliers and Price of Diethyl 2-(phenylcarbamoyl)propanedioate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
DIETHYL BENZAMIDOMALONATE AldrichCPR
250MG
$ 33.40

Crysdot
Diethyl2-benzamidomalonate 98%
25g
$ 357.00

American Custom Chemicals Corporation
1,3-DIETHYL 2-(PHENYLFORMAMIDO)PROPANEDIOATE 95.00%
5G
$ 1005.43

American Custom Chemicals Corporation
1,3-DIETHYL 2-(PHENYLFORMAMIDO)PROPANEDIOATE 95.00%
2.5G
$ 852.21

American Custom Chemicals Corporation
1,3-DIETHYL 2-(PHENYLFORMAMIDO)PROPANEDIOATE 95.00%
1G
$ 648.81

Alichem
Diethyl2-benzamidomalonate
25g
$ 400.00

AHH
DIETHYL BENZAMIDOMALONATE 98%
50g
$ 297.00

Total 10 raw suppliers

Chemical Property of Diethyl 2-(phenylcarbamoyl)propanedioate

Chemical Property:

Vapor Pressure:3.82E-08mmHg at 25°C
Melting Point:60-61°C
Boiling Point:452.9°Cat760mmHg
Flash Point:227.7°C
PSA：81.70000
Density:1.182g/cm³
LogP:1.30210
Storage Temp.:2-8°C
XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:8
Exact Mass:279.11067264
Heavy Atom Count:20
Complexity:332

Purity/Quality:

97% ^*data from raw suppliers

DIETHYL BENZAMIDOMALONATE AldrichCPR ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 22-24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(C(=O)NC1=CC=CC=C1)C(=O)OCC

Technology Process of Diethyl 2-(phenylcarbamoyl)propanedioate

There total 21 articles about Diethyl 2-(phenylcarbamoyl)propanedioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 64-17-5
ethanol

: 4504-12-5
ethyl 5-oxo-2-phenyl-2,5-dihydroisoxazole-4-carboxaldehyde

: 16798-45-1
diethyl phenylcarbamoylmalonate

Guidance literature:: Irradiation;
DOI:10.1016/S0040-4020(01)82002-0

Reference yield: 85.0%

: 103-71-9
phenyl isocyanate

: 685-87-0
Diethyl 2-bromomalonate

: 16798-45-1
diethyl phenylcarbamoylmalonate

Guidance literature:: With indium; In dichloromethane; at 40 ℃; for 24h; Inert atmosphere; Sealed tube;
DOI:10.1055/s-0035-1561973

Reference yield: 82.0%

: 124-38-9,18923-20-1
carbon dioxide

: 2325-27-1
N-phenyltriphenyliminophosphorane

: 105-53-3
diethyl malonate

: 16798-45-1
diethyl phenylcarbamoylmalonate

Guidance literature:: diethyl malonate; With lithium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃; for 2h;

carbon dioxide; N-phenyltriphenyliminophosphorane; With 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; Reflux;
DOI:10.1039/d1cc01016f