(5E)-N,N,6-trimethyl-5-[[3-(trifluoromethyl)phenyl]methylidene]-4H-pyridazin-3-amine

Base Information

Chemical Name:(5E)-N,N,6-trimethyl-5-[[3-(trifluoromethyl)phenyl]methylidene]-4H-pyridazin-3-amine
CAS No.:99300-77-3
Molecular Formula:C15H16 F3 N3
Molecular Weight:295.3
Hs Code.:

Synonyms:3-dimethylamino-5-(3'-trifluoromethyl)-6-methyl(4H)-pyridazine;PC 88;PC-88

Suppliers and Price of (5E)-N,N,6-trimethyl-5-[[3-(trifluoromethyl)phenyl]methylidene]-4H-pyridazin-3-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of (5E)-N,N,6-trimethyl-5-[[3-(trifluoromethyl)phenyl]methylidene]-4H-pyridazin-3-amine

Chemical Property:

Vapor Pressure:1.37E-05mmHg at 25°C
Boiling Point:367.4°Cat760mmHg
Flash Point:176°C
PSA：27.96000
Density:1.18g/cm³
LogP:2.69970
XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:295.12963201
Heavy Atom Count:21
Complexity:475

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NN=C(CC1=CC2=CC(=CC=C2)C(F)(F)F)N(C)C
Isomeric SMILES:CC\1=NN=C(C/C1=C\C2=CC(=CC=C2)C(F)(F)F)N(C)C

Technology Process of (5E)-N,N,6-trimethyl-5-[[3-(trifluoromethyl)phenyl]methylidene]-4H-pyridazin-3-amine

There total 3 articles about (5E)-N,N,6-trimethyl-5-[[3-(trifluoromethyl)phenyl]methylidene]-4H-pyridazin-3-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 105826-58-2
6-Chloro-3-methyl-4-[1-(3-trifluoromethyl-phenyl)-meth-(E)-ylidene]-4,5-dihydro-pyridazine

: 124-40-3
dimethyl amine

: 99300-77-3
Dimethyl-{6-methyl-5-[1-(3-trifluoromethyl-phenyl)-meth-(E)-ylidene]-4,5-dihydro-pyridazin-3-yl}-amine

Guidance literature:: In water; at 160 ℃; for 6h;
DOI:10.1002/jhet.5570220630

Reference yield:

: 90060-90-5
5-[Hydroxy-(3-trifluoromethyl-phenyl)-methyl]-6-methyl-4,5-dihydro-2H-pyridazin-3-one

: 99300-77-3
Dimethyl-{6-methyl-5-[1-(3-trifluoromethyl-phenyl)-meth-(E)-ylidene]-4,5-dihydro-pyridazin-3-yl}-amine

Guidance literature:: Multi-step reaction with 2 steps

1: POCl₃ / 1.5 h / Heating

2: 95 percent / H₂O / 6 h / 160 °C

With trichlorophosphate; In water;
DOI:10.1002/jhet.5570220630

Reference yield:

: 90060-95-0
6-Methyl-5-[1-(3-trifluoromethyl-phenyl)-meth-(E)-ylidene]-4,5-dihydro-2H-pyridazin-3-one

: 99300-77-3
Dimethyl-{6-methyl-5-[1-(3-trifluoromethyl-phenyl)-meth-(E)-ylidene]-4,5-dihydro-pyridazin-3-yl}-amine

Guidance literature:: Multi-step reaction with 2 steps

1: 63 percent / POCl₃ / 1.5 h / Heating

2: 95 percent / H₂O / 6 h / 160 °C

With trichlorophosphate; In water;
DOI:10.1002/jhet.5570220630