N-(2-acetylphenyl)-2-phenylacetamide

Base Information

• Chemical Name: N-(2-acetylphenyl)-2-phenylacetamide
• CAS No.: 41296-66-6
• Molecular Formula: C16H15NO2
• Molecular Weight: 253.2958
• Hs Code.: 2924299090
• Mol file: 41296-66-6.mol

Synonyms:Phenacetamido-2 acetophenone;Phenyl-essigsaeure-(2-acetyl-anilid);Benzeneacetamide,N-(2-acetylphenyl);2-Phenacetamino-acetophenon;2'-acetyl-1-phenylacetanilide;N-(2-Acetylphenyl)benzeneacetamide;o-acetyl-N-(phenylacetyl)aniline;Phenacetamido-2 acetophenone [French];phenyl-acetic acid-(2-acetyl-anilide);

Chemical Property of N-(2-acetylphenyl)-2-phenylacetamide

Chemical Property:

• Vapor Pressure: 3.4E-09mmHg at 25°C
• Boiling Point: 475.1°Cat760mmHg
• Flash Point: 187.6°C
• PSA: 49.66000
• Density: 1.179g/cm³
• LogP: 3.71990

Purity/Quality:

N-(2-ACETYLPHENYL)-2-PHENYLACETAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-(2-acetylphenyl)-2-phenylacetamide

There total 2 articles about N-(2-acetylphenyl)-2-phenylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

phenylacetic acid (103-82-2) + 2-aminoacetophenone (551-93-9) → 2'-acetyl-1-phenylacetanilide (41296-66-6)

Guidance literature:

With bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride; triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 48h; Inert atmosphere;

DOI:10.1002/cmdc.201200551

Reference yield:

2-aminoacetophenone (551-93-9) + phenylacetyl chloride (103-80-0) → 2'-acetyl-1-phenylacetanilide (41296-66-6)

Guidance literature:

With diethyl ether;

Reference yield: 80.0%

2'-acetyl-1-phenylacetanilide (41296-66-6) → 4-methyl-3-phenylquinolin-2(1H)-one (19069-84-2)

Guidance literature:

With sodium; In toluene; for 1h; Heating;

DOI:10.1021/jm00395a013

upstream raw materials:

2-aminoacetophenone

phenylacetyl chloride

phenylacetic acid

Downstream raw materials:

4-methyl-3-phenyl-quinolin-2-ol

4-methyl-3-phenylquinolin-2(1H)-one

2-benzyl-4-methyl-quinazoline

2-chloro-4-methyl-3-phenylquinoline