9-(methylsulfanyl)acridine

Base Information

• Chemical Name: 9-(methylsulfanyl)acridine
• CAS No.: 951-08-6
• Molecular Formula: C14H11NS
• Molecular Weight: 225.314
• Mol file: 951-08-6.mol

Synonyms:

Chemical Property of 9-(methylsulfanyl)acridine

Chemical Property:

• Vapor Pressure: 1E-06mmHg at 25°C

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 9-(methylsulfanyl)acridine

There total 6 articles about 9-(methylsulfanyl)acridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

acridine-9-thione (6540-78-9) + dimethyl sulfate (77-78-1) → 9-(methylthio)acridine (951-08-6)

Guidance literature:

With sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; In dichloromethane; at 0 - 5 ℃; for 0.25h;

DOI:10.1055/s-1980-29237

Reference yield: 87.0%

acridine-9-thione (6540-78-9) + methyl iodide (74-88-4) → 9-(methylthio)acridine (951-08-6)

Guidance literature:

N-benzyl-N,N,N-triethylammonium chloride; In potassium hydroxide; toluene; for 2h; Heating;

Reference yield: 81.0%

9-Chloroacridine (1207-69-8) + sodium thiomethoxide (5188-07-8) → 9-(methylthio)acridine (951-08-6)

Guidance literature:

In methanol; for 4h;

DOI:10.1139/v82-066

upstream raw materials:

acridine-9-thione

methyl iodide

9-Chloroacridine

sodium thiomethoxide

Downstream raw materials:

methylthiol

10H-acridin-9-one

Refernces

The First Total Synthesis of the Antimicrobial Sesquiterpenes (±)-Enokipodins A and B

10.1055/s-2003-45003

The study reports the first total synthesis of antimicrobial sesquiterpenes (±)-enokipodins A and B, along with the formal total synthesis of cuparene-1,4-diol and cuparene-1,4-quinone. The synthesis starts from 2,5-dimethoxy-4-methylacetophenone, using Claisen rearrangement and ring-closing metathesis as key steps. Enokipodins A and B exhibit significant antimicrobial activity against certain fungi and bacteria. The study aims to develop a methodology for synthesizing these compounds due to their interesting biological properties.