(2E)-3-(1,3-benzodioxol-5-yl)acryloyl chloride

Base Information

• Chemical Name: (2E)-3-(1,3-benzodioxol-5-yl)acryloyl chloride
• CAS No.: 96249-87-5
• Molecular Formula: C10H7ClO3
• Molecular Weight: 210.617
• Mol file: 96249-87-5.mol

Synonyms:trans-3-benzo[1,3]dioxol-5-yl-acryloyl chloride;3-(benzo-[1,3]dioxol-5-yl)acroyl chloride;3,4-(methylenedioxy)cinnamoyl chloride;3,4-(methylenedioxy)-cinnamoyl chloride;(E)-3,4-methylendioxycinnamic chloride;3,4-methylenedioxy cinnamoyl chloride;(E)-3-(1,3-benzodioxol-5-yl)acryloyl chloride;

Chemical Property of (2E)-3-(1,3-benzodioxol-5-yl)acryloyl chloride

Chemical Property:

• PSA: 35.53000
• LogP: 2.19390

Purity/Quality:

99%, ^*data from raw suppliers

3-(1,3-Benzodioxol-5-yl)acryloylchloride 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (2E)-3-(1,3-benzodioxol-5-yl)acryloyl chloride

There total 15 articles about (2E)-3-(1,3-benzodioxol-5-yl)acryloyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

3,4-methylenedioxy-trans-cinnamic acid (2373-80-0,38489-76-8) → (E)-3-(1,3-benzodioxol-5-yl)acryloyl chloride (96249-87-5)

Guidance literature:

With oxalyl dichloride; at 25 ℃; for 0.5h;

DOI:10.1016/j.bmcl.2004.04.019

Reference yield: 98.0%

oxalyl dichloride (79-37-8) + 3,4-methylenedioxy-trans-cinnamic acid (2373-80-0,38489-76-8) → (E)-3-(1,3-benzodioxol-5-yl)acryloyl chloride (96249-87-5)

Guidance literature:

In N-methyl-acetamide; dichloromethane;

Reference yield: 42.0%

3,4-(methylenedioxy)cinnamic acid (2373-80-0,38489-76-8) → 3-benzo[1,3]dioxol-5-yl-acryloyl chloride (96249-87-5,26930-49-4) + 3-chloro-5,6-methylenedioxybenzothiophene-2-carbonyl chloride (137278-46-7)

Guidance literature:

With pyridine; thionyl chloride; In N,N-dimethyl-formamide; Yields of byproduct given; 1.) reflux, 4 h, 2.) 140-150 deg C, 1 h;

DOI:10.1007/BF00824304

upstream raw materials:

3,4-methylenedioxy-trans-cinnamic acid

piperonal

oxalyl dichloride

3,4-dihydroxybenzaldehyde

Downstream raw materials:

2-((E)-3-Benzo[1,3]dioxol-5-yl-acryloylamino)-3-phenyl-propionic acid

1-(benzoyloxy)-5-<((E)-piperonylacryloyl)oxy>-1(E),3(E)-pentadiene

(E)-3-(benzo[d][1,3]dioxol-5-yl)-N,N-dimethylacrylamide

α-(3,4-methylenedioxycinnamoyl)benzylidene(triphenyl)phosphorane

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 96249-87-5 (2E)-3-(1,3-benzodioxol-5-yl)acryloyl chloride

Send

Send

Metric Ton KG G Pound L ML

Send

Send