6-Chloro-1,3-dihydropyrrolo[3,2-B]pyridin-2-one

Base Information

Chemical Name:6-Chloro-1,3-dihydropyrrolo[3,2-B]pyridin-2-one
CAS No.:136888-12-5
Molecular Formula:C7H5ClN2O
Molecular Weight:168.583
Hs Code.:2933990090
DSSTox Substance ID:DTXSID70440656
Wikidata:Q72518533
Mol file:136888-12-5.mol

Synonyms:136888-12-5;6-CHLORO-1,3-DIHYDROPYRROLO[3,2-B]PYRIDIN-2-ONE;6-chloro-4-azaoxindole;6-CHLORO-4-AZA-2-OXINDOLE;6-CHLORO-1H,2H,3H-PYRROLO[3,2-B]PYRIDIN-2-ONE;6-Chloro-4-azaindoline-2-one;MFCD02179618;SCHEMBL658962;AMY2844;DTXSID70440656;QKOHTVGXLOSROT-UHFFFAOYSA-N;AKOS015949498;PB21798;AS-34893;SY033632;CS-0050243;FT-0684929;A886608;6-CHLORO-1,3-DIHYDRO-2H-PYRROLO[3,2-B]PYRIDIN-2-ONE

Suppliers and Price of 6-Chloro-1,3-dihydropyrrolo[3,2-B]pyridin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-Chloro-1H-pyrrolo[3,2-B]pyridin-2(3H)-one
5g
$ 60.00

SynQuest Laboratories
6-Chloro-4-aza-2-oxindoie
1 g
$ 760.00

Matrix Scientific
6-Chloro-1,3-dihydropyrrolo[3,2-b]pyridin-2-one >95%
1g
$ 1500.00

Matrix Scientific
6-Chloro-1,3-dihydropyrrolo[3,2-b]pyridin-2-one >95%
500mg
$ 870.00

Crysdot
6-Chloro-1H-pyrrolo[3,2-b]pyridin-2(3H)-one 95+%
1g
$ 320.00

Chemenu
6-chloro-1H,2H,3H-pyrrolo[3,2-b]pyridin-2-one 95%+
10g
$ 1375.00

Chemenu
6-chloro-1H,2H,3H-pyrrolo[3,2-b]pyridin-2-one 95%+
5g
$ 836.00

Chemenu
6-chloro-1H,2H,3H-pyrrolo[3,2-b]pyridin-2-one 95%+
1g
$ 240.00

Chemcia Scientific
6-Chloro-1,3-dihydro-pyrrolo[3,2-b]pyridin-2-one 95%
1 G
$ 375.00

Alichem
6-Chloro-1H-pyrrolo[3,2-b]pyridin-2(3H)-one
5g
$ 1783.60

Total 25 raw suppliers

Chemical Property of 6-Chloro-1,3-dihydropyrrolo[3,2-B]pyridin-2-one

Chemical Property:

Boiling Point:333.8±42.0 °C(Predicted)
PKA:12.03±0.20(Predicted)
PSA：41.99000
Density:1.450
LogP:1.36760
Storage Temp.:2-8°C
XLogP3:0.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:168.0090405
Heavy Atom Count:11
Complexity:185

Purity/Quality:

99%, ^*data from raw suppliers

6-Chloro-1H-pyrrolo[3,2-B]pyridin-2(3H)-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C2=C(C=C(C=N2)Cl)NC1=O

Technology Process of 6-Chloro-1,3-dihydropyrrolo[3,2-B]pyridin-2-one

There total 8 articles about 6-Chloro-1,3-dihydropyrrolo[3,2-B]pyridin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: ethyl (5-chloro-3-nitropyridin-2-yl)acetate

: 136888-12-5
6-chloro-1,3-dihydro-2H-pyrrolo[3,2-b]pyridin-2-one

Guidance literature:: With water; ammonium chloride; zinc; In ethanol; at 100 ℃; for 48h;

Reference yield:

: 144-55-8
sodium hydrogencarbonate

: 136888-12-5
6-chloro-1,3-dihydro-2H-pyrrolo[3,2-b]pyridin-2-one

Guidance literature:

Reference yield:

: 136888-13-6
diethyl (5-chloro-3-nitropyridin-2-yl )propanedioate

: 136888-12-5
6-chloro-1,3-dihydro-2H-pyrrolo[3,2-b]pyridin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 12.6 g / H₂ / Ra Ni / ethanol; H₂O / 4 h / 2280 Torr

2: 6 N aq. HCl / 4 h / Heating

With hydrogenchloride; hydrogen; nickel; In ethanol; water;
DOI:10.1002/jhet.5570330213