2-Amino-5-chloro-3-nitropyridine

Base Information

• Chemical Name: 2-Amino-5-chloro-3-nitropyridine
• CAS No.: 5409-39-2
• Molecular Formula: C5H4ClN3O2
• Molecular Weight: 173.559
• Hs Code.: 29333999
• Mol file: 5409-39-2.mol

Synonyms:2-Amino-5-Chloro-3-Nitropyridine;5-Chloro-3-nitropyridin-2-amine;5-CHLORO-3-NITROPYRIDIN-2-AMINE;5-chloro-3-nitro-2-pyridineamine;2-Amino-5-chloro-3-nitrpyridine;2-amino-3-nitro-5-chloropyridine;2-PYRIDINAMINE,5-CHLORO-3-NITRO;5-CHLORO-3-NITRO-PYRIDIN-2-YLAMINE;5-Chloro-3-nitro-2-aminopyridine;

Chemical Property of 2-Amino-5-chloro-3-nitropyridine

Chemical Property:

• Appearance/Colour: yellow crystalline powder
• Vapor Pressure: 0.000805mmHg at 25°C
• Melting Point: 193-197 °C(lit.)
• Boiling Point: 305.8 °C at 760 mmHg
• PKA: 0.17±0.49(Predicted)
• Flash Point: 138.7 °C
• PSA: 84.73000
• Density: 1.596 g/cm³
• LogP: 2.32980
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Solubility.: soluble in Dimethylformamide

Purity/Quality:

99.9% ^*data from raw suppliers

2-Amino-5-chloro-3-nitropyridine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi, Xn
• Hazard Codes: Xi,Xn
• Statements: 36/37/38-20/21/22
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of 2-Amino-5-chloro-3-nitropyridine

There total 11 articles about 2-Amino-5-chloro-3-nitropyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

5-chloro-2-pyridylamine (1072-98-6) → 2-amino-5-chloro-3-nitropyridine (5409-39-2)

Guidance literature:

With sulfuric acid; nitric acid; at 55 - 59 ℃; for 1h;

DOI:10.1080/00397911.2011.566408

Reference yield: 58.0%

1,1-diamino-2-nitroethene (71090-35-2) + N-[(2Z)-2-chloro-3-(dimethylamino)prop-2-en-1-ylidene]-N-methylmethanaminium perchlorate → 2-amino-5-chloro-3-nitropyridine (5409-39-2)

Guidance literature:

In butan-1-ol; for 4h; Heating;

DOI:10.1016/j.bmc.2004.03.023

Reference yield: 8.5%

5-chloro-2-nitraminopyridine (31396-27-7) → 2-amino-5-chloro-3-nitropyridine (5409-39-2)

Guidance literature:

In methanol; for 0.666667h; Quantum yield; Irradiation;

upstream raw materials:

5-chloro-2-nitraminopyridine

5-chloro-2-pyridylamine

sulfuric acid

nitric acid

Downstream raw materials:

2,3-Diaminopyridine

5-chloro-2,3-diaminopyridine

5,6-dichloropyridine-2,3-diamine

2,5-dichloro-3-nitropyridine