2,3-Diphenylsuccinic acid

Base Information

• Chemical Name: 2,3-Diphenylsuccinic acid
• CAS No.: 7584-72-7
• Molecular Formula: C16H14 O4
• Molecular Weight: 270.285
• Hs Code.: 2917399090
• European Community (EC) Number: 214-953-7,659-979-3
• DSSTox Substance ID: DTXSID20997221
• Nikkaji Number: J519.001K
• Mol file: 7584-72-7.mol

Synonyms:2,3-Diphenylsuccinic acid;7584-72-7;2,3-diphenylbutanedioic acid;2,3-DIPHENYLSUCCINICACID;Butanedioic acid, 2,3-diphenyl-;racemic-2,3-Diphenylbutanedioic acid;CBMicro_004760;Cambridge id 5105968;Oprea1_154473;SCHEMBL659768;2,3-diphenyl-butanedioic acid;Succinic acid, 2,3-diphenyl-;DTXSID20997221;PVXCQHHWNDJIJP-UHFFFAOYSA-N;21037-34-3;SMSF0003268;EINECS 214-953-7;NSC 75627;STK325150;(R*,S*)-2,3-Diphenylsuccinic acid;.alpha.,.beta.-Diphenylsuccinic acid;CB07070;BIM-0004755.P001;CS-0331131;FT-0605179;FT-0715208;(R,R)-(-)-2,3-DIPHENYLSUCCINICACID;Butanedioic acid, 2,3-diphenyl-, (R*,S*)-;SR-01000195377;SR-01000195377-1

Chemical Property of 2,3-Diphenylsuccinic acid

Chemical Property:

• Melting Point: 211.5 °C(Solv: benzene (71-43-2))
• Boiling Point: 360.2±37.0 °C(Predicted)
• PKA: 3.38±0.10(Predicted)
• PSA: 74.60000
• Density: 1.307±0.06 g/cm3(Predicted)
• LogP: 2.72320
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 270.08920892
• Heavy Atom Count: 20
• Complexity: 306

Purity/Quality:

99% ^*data from raw suppliers

2,3-Diphenylsuccinicacid 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(C(C2=CC=CC=C2)C(=O)O)C(=O)O

Technology Process of 2,3-Diphenylsuccinic acid

There total 115 articles about 2,3-Diphenylsuccinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

phenylacetic acid (103-82-2) + diethyl ether (60-29-7,927820-24-4) → 2,3-diphenylsuccinic acid (7584-72-7) + MANDELIC ACID (611-71-2,611-72-3,17199-29-0,90-64-2)

Guidance literature:

at 0 ℃;

Reference yield:

sodium phenylacetate (114-70-5) → meso-2,3-diphenylsuccinic acid (7584-72-7,21037-34-3,41915-64-4,47039-46-3,74431-38-2,1225-13-4) + MANDELIC ACID (611-71-2,611-72-3,17199-29-0,90-64-2)

Guidance literature:

With diethyl ether; isopropylmagnesium bromide; anschliessend Behandeln mit Sauerstoff;

Reference yield:

carbon dioxide (124-38-9,18923-20-1) + diphenyl acetylene (501-65-5) → stilbene (588-59-0) + (E)-2,3-diphenylpropenoic acid (91-48-5) + 2,3-diphenylsuccinic acid (7584-72-7)

Guidance literature:

With tetrabutylammonium tetrafluoroborate; tris(2,2'-bipyridine)nickel(II) tetrafluoroborate; In N,N-dimethyl-formamide; at 80 ℃; for 15h; Yield given. Yields of byproduct given; electrochemical reaction, 50 mA applied between a Mg anode and a carbon fiber cathode;

DOI:10.1016/0022-328X(89)87156-6

upstream raw materials:

phenylacetic acid

Ethyl 2-phenylethanoate

carbon dioxide

diphenyl acetylene

Downstream raw materials:

(2S,3S)-(+)-2,3-Diphenylsuccinic acid

cis-4b,5,9b,10-tetrahydroindeno<2,1-a>indene-5,10-dione bis

indenoindene

(+/-)(4br,9bc)-4b,5,9b,10-tetrahydro-indeno[2,1-a]indene