1,3,2-Dioxaphosphorinane, 2-chloro-4-methyl-

Base Information

• Chemical Name: 1,3,2-Dioxaphosphorinane, 2-chloro-4-methyl-
• CAS No.: 6362-87-4
• Molecular Formula: C4H8ClO2P
• Molecular Weight: 154.533
• DSSTox Substance ID: DTXSID90979832
• Nikkaji Number: J1.678.781G
• Mol file: 6362-87-4.mol

Synonyms:1,3,2-Dioxaphosphorinane, 2-chloro-4-methyl-;6362-87-4;2-chloro-4-methyl-1,3,2-dioxaphosphinane;SCHEMBL8764243;DTXSID90979832;4-methyl-2-chloro-1,3,2-dioxaphosphorinane

Chemical Property of 1,3,2-Dioxaphosphorinane, 2-chloro-4-methyl-

Chemical Property:

• Vapor Pressure: 3.64mmHg at 25°C
• Boiling Point: 156.9°C at 760 mmHg
• Flash Point: 48.7°C
• XLogP3: 1.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 153.9950442
• Heavy Atom Count: 8
• Complexity: 80.4

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1CCOP(O1)Cl

Technology Process of 1,3,2-Dioxaphosphorinane, 2-chloro-4-methyl-

There total 9 articles about 1,3,2-Dioxaphosphorinane, 2-chloro-4-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

1.3-butanediol (18826-95-4,107-88-0) → 2-Chloro-4-methyl-1,3,2-dioxaphosphorinane (6362-87-4)

Guidance literature:

With 2,3-Dimethylaniline; phosphorus trichloride; In diethyl ether; at 0 ℃; for 2h;

DOI:10.1016/S0022-328X(01)01228-1

Reference yield: 59.0%

1.3-butanediol (18826-95-4,107-88-0) → trans-2-Chloro-4-methyl-1,3,2λ3-dioxaphosphorinane (6362-87-4,33643-15-1,93632-97-4)

Guidance literature:

With phosphorus trichloride; In dichloromethane;

DOI:10.1021/jo00121a041

Reference yield:

1.3-butanediol (18826-95-4,107-88-0) + phosphorus trichloride (7719-12-2,52843-90-0) → 2-Chloro-4-methyl-1,3,2-dioxaphosphorinane (6362-87-4)

Guidance literature:

With triethylamine;

upstream raw materials:

1.3-butanediol

pyridine

diethyl ether

phosphorus trichloride

Downstream raw materials:

4-methyl-2-methoxy-1,3,2-dioxaphosphorinane

(4-methyl-[1,3,2]dioxaphosphinan-2-yl)-phenyl-amine

4-methyl-2-phenylethynyl-[1,3,2]dioxaphosphinane

diphenylamide of 1,3-butylenecyclophosphorous acid