2-Methoxy-4-methyl-1,3,2-dioxaphosphorinane

Base Information

• Chemical Name: 2-Methoxy-4-methyl-1,3,2-dioxaphosphorinane
• CAS No.: 33892-95-4
• Molecular Formula: C5H11O3P
• Molecular Weight: 150.1128
• DSSTox Substance ID: DTXSID80955483
• Mol file: 33892-95-4.mol

Synonyms:2-Methoxy-4-methyl-1,3,2-dioxaphosphorinane;33892-95-4;2-methoxy-4-methyl-1,3,2-dioxaphosphinane;SCHEMBL8636245;DTXSID80955483

Chemical Property of 2-Methoxy-4-methyl-1,3,2-dioxaphosphorinane

Chemical Property:

• Vapor Pressure: 12.8mmHg at 25°C
• Boiling Point: 128.7°C at 760 mmHg
• Flash Point: 29.8°C
• XLogP3: 0.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 150.04458121
• Heavy Atom Count: 9
• Complexity: 88.3

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1CCOP(O1)OC

Technology Process of 2-Methoxy-4-methyl-1,3,2-dioxaphosphorinane

There total 15 articles about 2-Methoxy-4-methyl-1,3,2-dioxaphosphorinane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methanol (67-56-1) + 2-Chloro-4-methyl-1,3,2-dioxaphosphorinane (6362-87-4) → 4-methyl-2-methoxy-1,3,2-dioxaphosphorinane (33892-95-4)

Guidance literature:

With pyridine;

Reference yield:

bis(diethylamino)chlorophosphine (685-83-6) + 2-(1-imidazolyl)-4-methyl-1,3,2-dioxaphosphorinane (128592-04-1) → 4-methyl-2-methoxy-1,3,2-dioxaphosphorinane (33892-95-4)

Guidance literature:

In 1,4-dioxane; for 0.0833333h;

Reference yield:

1.3-butanediol (18826-95-4,107-88-0) + phosphorous acid trimethyl ester (121-45-9) → 4-methyl-2-methoxy-1,3,2-dioxaphosphorinane (33892-95-4)

Guidance literature:

upstream raw materials:

pyridine

methanol

2-Chloro-4-methyl-1,3,2-dioxaphosphorinane

N,N-dimethyl-aniline

Downstream raw materials:

2-benzyl-4-methyl-[1,3,2]dioxaphosphinane-2-oxide

4-methyl-2-trityl-[1,3,2]dioxaphosphinin-2-oxide

(4-Methyl-2-oxo-2λ⁵-[1,3,2]dioxaphosphinan-2-yl)-phenyl-methanone