1,3-Dioxolo(4,5-g)quinoline-7-carboxylic acid, 5,8-dihydro-9-amino-5-ethyl-8-oxo-

Base Information

Chemical Name:1,3-Dioxolo(4,5-g)quinoline-7-carboxylic acid, 5,8-dihydro-9-amino-5-ethyl-8-oxo-
CAS No.:51624-54-5
Molecular Formula:C13H12N2O5
Molecular Weight:276.2448
Hs Code.:
DSSTox Substance ID:DTXSID30199572
Nikkaji Number:J610.528I
Wikidata:Q83072476

Synonyms:Amino-oxolinic acid;BRN 0562097;1,3-Dioxolo(4,5-g)quinoline-7-carboxylic acid, 5,8-dihydro-9-amino-5-ethyl-8-oxo-;5,8-Dihydro-9-amino-5-ethyl-8-oxo-1,3-dioxolo(4,5-g)quinoline-7-carboxylic acid;51624-54-5;SCHEMBL14845099;DTXSID30199572;DZKGUVVWZUCSJU-UHFFFAOYSA-N;LS-62841;1,3-Dioxolo[4,5-g]quinoline-7-carboxylic acid, 9-amino-5-ethyl-5,8-dihydro-8-oxo-;1-Ethyl-1,4-dihydro-4-oxo-5-amino-6,7-methylenebisoxy-3-quinolinecarboxylic acid;9-amino-5-ethyl-8-oxo-5,8-dihydro-[1,3]dioxolo[4,5-g]quinoline-7-carboxylic acid

Suppliers and Price of 1,3-Dioxolo(4,5-g)quinoline-7-carboxylic acid, 5,8-dihydro-9-amino-5-ethyl-8-oxo-

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1,3-Dioxolo(4,5-g)quinoline-7-carboxylic acid, 5,8-dihydro-9-amino-5-ethyl-8-oxo-

Chemical Property:

Vapor Pressure:6.06E-13mmHg at 25°C
Boiling Point:550.3°Cat760mmHg
Flash Point:286.6°C
Density:1.548g/cm³
XLogP3:1.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:2
Exact Mass:276.07462149
Heavy Atom Count:20
Complexity:477

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN1C=C(C(=O)C2=C(C3=C(C=C21)OCO3)N)C(=O)O

Technology Process of 1,3-Dioxolo(4,5-g)quinoline-7-carboxylic acid, 5,8-dihydro-9-amino-5-ethyl-8-oxo-

There total 4 articles about 1,3-Dioxolo(4,5-g)quinoline-7-carboxylic acid, 5,8-dihydro-9-amino-5-ethyl-8-oxo- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 51624-70-5
5-ethyl-9-nitro-8-oxo-5,8-dihydro-[1,3]dioxolo[4,5-a]quinolin-7-carboxylic acid

: 51624-54-5
9-amino-5-ethyl-8-oxo-5,8-dihydro-[1,3]dioxolo[4,5-g]quinolin-7-carboxylic acid

Guidance literature:: With hydrogenchloride; palladium on activated charcoal; hydrogen; acetic acid; for 1h; under 2585.81 Torr;

Reference yield:

: 16172-03-5
ethyl 5-ethyl-5,8-dihydro-8-oxo-1,3-dioxolo<4,5-g>quinoline-7-carboxylate

: 51624-54-5
9-amino-5-ethyl-8-oxo-5,8-dihydro-[1,3]dioxolo[4,5-g]quinolin-7-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: KNO₃, H₂SO₄ / 1 h / 10 °C

2: KOH / ethanol / 1 h / Heating

3: H₂ / Pd-C / acetic acid; aq. HCl / 760 Torr

With potassium hydroxide; sulfuric acid; hydrogen; potassium nitrate; palladium on activated charcoal; In hydrogenchloride; ethanol; acetic acid;

Reference yield:

: 70768-87-5
5-ethyl-9-nitro-8-oxo-5,8-dihydro-[1,3]dioxolo[4,5-g]quinoline-7-carboxylic acid ethyl ester

: 51624-54-5
9-amino-5-ethyl-8-oxo-5,8-dihydro-[1,3]dioxolo[4,5-g]quinolin-7-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: KOH / ethanol / 1 h / Heating

2: H₂ / Pd-C / acetic acid; aq. HCl / 760 Torr

With potassium hydroxide; hydrogen; palladium on activated charcoal; In hydrogenchloride; ethanol; acetic acid;