Vitride

Base Information

• Chemical Name: Vitride
• CAS No.: 22722-98-1
• Molecular Formula: C6H16AlNaO4
• Molecular Weight: 202.162
• Hs Code.: 29319090
• DSSTox Substance ID: DTXSID90894051
• Wikidata: Q416467
• Mol file: 22722-98-1.mol

Synonyms:dihydrobis(2-methoxyethoxy)aluminate;Red-Al;Vitride

Chemical Property of Vitride

Chemical Property:

• Appearance/Colour: clear to slightly hazy, colorless to light amber
• Vapor Pressure: 21 mm Hg ( 20 °C)
• Melting Point: 112oC
• Boiling Point: 396-402°C
• Flash Point: 40 °F
• PSA: 36.92000
• Density: 1.036 g/mL at 25 °C
• LogP: 0.45240
• Storage Temp.: Flammables area
• Sensitive.: Air & Moisture Sensitive
• Solubility.: Miscible with aromatic hydrocarbons, ether, tetrahydrofuran, dim
• Water Solubility.: reacts
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 8
• Exact Mass: 202.0761667
• Heavy Atom Count: 12
• Complexity: 63.6

Purity/Quality:

70%, ^*data from raw suppliers

SodiumBis(2-methoxyethoxy)aluminiumhydride(60%intoluene) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F, C
• Hazard Codes: F,C
• Statements: 11-14/15-34-48/20-63-65-67
• Safety Statements: 26-36/37/39-43-45-62-46-16-9

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: COCCO[AlH2-]OCCOC.[Na+]
• Uses: Reducing agent. Sodium bis(2-methoxyethoxy)aluminum hydride acts as a reducing agent in organic synthesis. It is used to prepare azoxyarenes, azoarenes and hydroazoarenes from nitroarenes. It plays an important role for the conversion of aldehydes, ketones, carboxylic acids, esters, acyl halides and anhydrides to primary alcohols. It is also employed in hydroaluminate alkenes and alkynes. It is utilized in the reduction of lactones and epoxides into diols. Further, it serves as a methylation reagent for aryl-activated compounds. In addition to this, it is involved in the reduction of amides, nitriles and amines to the corresponding amines. Red-Al? sodium bis(2-methoxyethoxy)aluminum hydride can be used as: ?????? A tosyl deprotecting agent.??????? A catalyst for crosslinking of polyvinylsilanes (PVS) by Si-Si dehydrocoupling reaction in the presence of group 4 metallocene complexes.??????? A reducing reagent for the synthesis of optically active N-protected amino alcohols and peptide alcohols.

Refernces

Stereochemistry of contiguous cyclopropane formation from cascade cyclization of a skipped dienyl homoallyl triflate

10.1039/b412811g

The research discusses the stereochemistry involved in the formation of contiguous cyclopropanes through cascade cyclization of a skipped dienyl homoallyl triflate. The study aims to understand the role of double bond geometry in the cyclization process and to determine the absolute stereochemistry of the reaction. The experiments involve the solvolysis of asymmetric homoallylic triflates, which bear a terminal stannyl substituent, to produce disubstituted cyclopropanes and bicyclopropanes with high enantiopurity. Key reactants include homoallylic triflates with a triflate leaving group at one end and a cation-stabilizing tin group at the other. The researchers synthesized various intermediates using a series of organic reactions, such as protection and deprotection of alcohols, reduction with Red-Al, and displacement with lithio tri-n-butylstannane. They also used tri?ic anhydride for solvolysis and analyzed the products through 1H NMR, HPLC on a chiral stationary phase, and X-ray crystallographic analysis to determine the stereochemistry and enantiomeric purity of the resulting cyclopropanes and bicyclopropanes.