Propanoic acid, 2,2-dimethyl-, 2-(7-chloro-2,3-dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)hydrazide

Base Information

Chemical Name:Propanoic acid, 2,2-dimethyl-, 2-(7-chloro-2,3-dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)hydrazide
CAS No.:84044-30-4
Molecular Formula:C20H21ClN4O2
Molecular Weight:384.8593
Hs Code.:
DSSTox Substance ID:DTXSID601004340

Synonyms:BRN 5141388;84044-30-4;Propanoic acid, 2,2-dimethyl-, 2-(7-chloro-2,3-dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)hydrazide;C20H21ClN4O2;DTXSID601004340;C20-H21-Cl-N4-O2;LS-121403;N-(7-Chloro-2-hydroxy-5-phenyl-3H-1,4-benzodiazepin-3-yl)-2,2-dimethylpropanehydrazonic acid

Suppliers and Price of Propanoic acid, 2,2-dimethyl-, 2-(7-chloro-2,3-dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)hydrazide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Propanoic acid, 2,2-dimethyl-, 2-(7-chloro-2,3-dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)hydrazide

Chemical Property:

Boiling Point:543.8°Cat760mmHg
Flash Point:282.7°C
Density:1.3g/cm³
XLogP3:4.1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:384.1353036
Heavy Atom Count:27
Complexity:595

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)C(=O)NNC1C(=O)NC2=C(C=C(C=C2)Cl)C(=N1)C3=CC=CC=C3

Technology Process of Propanoic acid, 2,2-dimethyl-, 2-(7-chloro-2,3-dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)hydrazide

There total 2 articles about Propanoic acid, 2,2-dimethyl-, 2-(7-chloro-2,3-dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 3282-30-2
pivaloyl chloride

: 75878-00-1
7-Chloro-5-phenyl-3-hydrazino-2,3-dihydro-1H-1,4-benzodiazepin-2-one

: 84044-30-4
7-Chloro-5-phenyl-3-pivaloyhydrazino-2,3-dihydro-1H-1,4-benzodiazepin-2-one

Guidance literature:: With pyridine; at 30 - 35 ℃; for 1h;
DOI:10.1007/BF00773096

Reference yield:

: 5358-44-1
3,7-dichloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepine-2-one

: 84044-30-4
7-Chloro-5-phenyl-3-pivaloyhydrazino-2,3-dihydro-1H-1,4-benzodiazepin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 78.5 percent / 85percent hydrazine hydrate / 0.5 h / 10 - 12 °C

2: 86 percent / pyridine / 1 h / 30 - 35 °C

With pyridine; hydrazine hydrate;
DOI:10.1007/BF00773096