N,N-Dimethylsulfamide

Base Information

• Chemical Name: N,N-Dimethylsulfamide
• CAS No.: 3984-14-3
• Molecular Formula: C2H8N2O2S
• Molecular Weight: 124.164
• Mol file: 3984-14-3.mol

Synonyms:dimethylsulfamide;N,N-DIMETHYLSULFAMIDE;N,N-DIMETHYLSULFAMOYLAMIDE;[methyl(sulfamoyl)amino]methane;N.N-DiMethylsu

Chemical Property of N,N-Dimethylsulfamide

Chemical Property:

• Appearance/Colour: White solid
• Vapor Pressure: 0.137mmHg at 25°C
• Melting Point: 95-96 °C
• Refractive Index: 1.502
• Boiling Point: 216.9 °C at 760 mmHg
• PKA: 11.41±0.60(Predicted)
• Flash Point: 85 °C
• PSA: 71.78000
• Density: 1.327 g/cm³
• LogP: 0.53260
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility.: Acetone (Slightly), DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

N,N-Dimethylsulfamide ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

• Uses: N,N-Dimethylsulfamide is a byproduct of Tolylfluanide (T536730) fungicide decomposition found in some waters. Upon ozonization it becomes a precursor for carcinogenic Nitrosodimethylamine (N525625). Otherwise N,N-Dimethylsulfamide is a versatile reactant used in various syntheses such as preparation of N-sulfonylbenzaldimines in copper-catalyzed aza-Friedel-Crafts reactions with 1-methylindole.

Technology Process of N,N-Dimethylsulfamide

There total 5 articles about N,N-Dimethylsulfamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

dimethylamino sulfonyl chloride (13360-57-1) → N,N-dimethylsulfamide (3984-14-3)

Guidance literature:

With ammonia; In methanol; at 60 ℃; for 16h; Sealed tube;

Reference yield:

dimethyl amine (124-40-3) → N,N-dimethylsulfamide (3984-14-3)

Guidance literature:

With SULFAMIDE; In 1,2-dimethoxyethane;

DOI:10.1021/jm00330a009

Reference yield:

N,N-Dimethyl-N'-(trimethylsilyl)sulfamid (29777-22-8) → N,N-dimethylsulfamide (3984-14-3)

Guidance literature:

With water; Heating;

DOI:10.1007/BF00911403

upstream raw materials:

dimethylamino sulfonyl chloride

N,N-Dimethyl-N'-(trimethylsilyl)sulfamid

dimethyl amine

Downstream raw materials:

3-nitro-N,N-dimethylbenzamide

N,N-dimethyl-2-phenylacetamide

N,N-dimethyl acetamide

N,N-dimethylbenzamide