2,5-Dihydro-2,5-dimethoxy-2,5-dimethylfuran

Base Information

• Chemical Name: 2,5-Dihydro-2,5-dimethoxy-2,5-dimethylfuran
• CAS No.: 18091-25-3
• Molecular Formula: C8H14 O3
• Molecular Weight: 158.197
• Hs Code.: 2932190090
• European Community (EC) Number: 241-995-3
• DSSTox Substance ID: DTXSID50885006
• Nikkaji Number: J260.874J
• Mol file: 18091-25-3.mol

Synonyms:2,5-dimethoxy-2,5-dimethylfuran;18091-25-3;2,5-Dihydro-2,5-dimethoxy-2,5-dimethylfuran;EINECS 241-995-3;Furan, 2,5-dihydro-2,5-dimethoxy-2,5-dimethyl-;2,5-dimethoxy-2,5-dimethyl-2,5-dihydrofuran;SCHEMBL10369706;DTXSID50885006;cis-2,5-dimethoxy-2,5-dimethyl-2,5-dihydrofuran

Chemical Property of 2,5-Dihydro-2,5-dimethoxy-2,5-dimethylfuran

Chemical Property:

• Vapor Pressure: 0.948mmHg at 25°C
• Boiling Point: 185.6°Cat760mmHg
• Flash Point: 58.7°C
• PSA: 27.69000
• Density: 1.01g/cm³
• LogP: 1.29800
• XLogP3: 0.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 158.094294304
• Heavy Atom Count: 11
• Complexity: 160

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1(C=CC(O1)(C)OC)OC

Technology Process of 2,5-Dihydro-2,5-dimethoxy-2,5-dimethylfuran

There total 4 articles about 2,5-Dihydro-2,5-dimethoxy-2,5-dimethylfuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,5-dimethylfuran (625-86-5) + methanol (67-56-1) → 2,5-dimethoxy-2,5-dimethyl-2,5-dihydro-furan (18091-25-3)

Guidance literature:

With bromine; sodium carbonate;

DOI:10.1021/jo01113a012

Reference yield:

methanol (67-56-1) + 2-methoxy-5-hydroperoxy-2,5-dimethylfuran (13249-74-6) → 2,5-dimethoxy-2,5-dimethyl-2,5-dihydro-furan (18091-25-3)

Guidance literature:

vanadia; for 20h; Yield given; Ambient temperature;

DOI:10.1016/S0040-4039(00)87227-5

Reference yield:

methanol (67-56-1) + (Z)-hex-3-ene-2,5-dione (17559-81-8) → 2,5-dimethoxy-2,5-dimethyl-2,5-dihydro-furan (18091-25-3)

Guidance literature:

for 3h; Ambient temperature;

DOI:10.1016/0040-4039(95)00828-Z

upstream raw materials:

2,5-dimethylfuran

methanol

2-methoxy-5-hydroperoxy-2,5-dimethylfuran

(Z)-hex-3-ene-2,5-dione

Downstream raw materials:

1-((1S,6R)-6-Acetyl-4-methyl-cyclohex-3-enyl)-ethanone

cis-4,5-diacetyl-cyclohexene

(Z)-hex-3-ene-2,5-dione

3,6-dimethylpyridazine

Refernces

• 1、 De Mico,Margarita,Piancatelli. "The binary reagent PhI(OAc)2-Mg(ClO4)2: a SET induced ring enlargement of furan derivatives into pyranones". . p. 3553 - 3556. Retrieved 2007/10/02.