2-([1,1'-Biphenyl]-4-yl)-1-phenylethanone

Base Information

Chemical Name:2-([1,1'-Biphenyl]-4-yl)-1-phenylethanone
CAS No.:27644-00-4
Molecular Formula:C20H16 O
Molecular Weight:272.346
Hs Code.:
NSC Number:167236
DSSTox Substance ID:DTXSID70304769
Nikkaji Number:J1.426.523F
Wikidata:Q82050957
Mol file:27644-00-4.mol

Synonyms:2-([1,1'-Biphenyl]-4-yl)-1-phenylethanone;27644-00-4;1-phenyl-2-(4-phenylphenyl)ethanone;2-([1,1'-Biphenyl]-4-yl)-1-phenylethan-1-one;NSC167236;Ethanone, 2-[1,1'-biphenyl]-4-yl-1-phenyl-;SCHEMBL1515725;Alpha,alpha-diphenyl acetophenone;DTXSID70304769;HZXXIQLDHPWKLO-UHFFFAOYSA-N;CBA64400;MFCD00998776;2-(biphenyl-4-yl)-1-phenylethanone;DS-8823;NSC-167236;CS-0149866;C74436;A913171

Suppliers and Price of 2-([1,1'-Biphenyl]-4-yl)-1-phenylethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of 2-([1,1'-Biphenyl]-4-yl)-1-phenylethanone

Chemical Property:

Vapor Pressure:7.3E-08mmHg at 25°C
Boiling Point:437.7°Cat760mmHg
Flash Point:192.3°C
Density:1.102g/cm³
XLogP3:4.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:4
Exact Mass:272.120115130
Heavy Atom Count:21
Complexity:315

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=CC=C(C=C2)CC(=O)C3=CC=CC=C3

Technology Process of 2-([1,1'-Biphenyl]-4-yl)-1-phenylethanone

There total 18 articles about 2-([1,1'-Biphenyl]-4-yl)-1-phenylethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 100-59-4
phenylmagnesium chloride

: 2-([1,1'-biphenyl]-4-yl)-1-morpholinoethan-1-one

: 27644-00-4
2-([1,1'-biphenyl]-4-yl)-1-phenylethanone

Guidance literature:: phenylmagnesium chloride; With lanthanium (III) chloride bis(lithium chloride) complex; In tetrahydrofuran; at -20 ℃; for 1.5h; Inert atmosphere;

2-([1,1'-biphenyl]-4-yl)-1-morpholinoethan-1-one; In tetrahydrofuran; at -78 ℃; for 2.5h; Inert atmosphere;
DOI:10.1002/anie.201405036

Reference yield: 94.0%

: 644-08-6
4-Methylbiphenyl

: 20383-28-2
N,N-diisopropyl benzamide

: 27644-00-4
2-([1,1'-biphenyl]-4-yl)-1-phenylethanone

Guidance literature:: With lithium diisopropyl amide; In tetrahydrofuran; at 60 ℃; for 12h;
DOI:10.1007/s11426-021-1035-5

Reference yield: 89.0%

: 644-08-6
4-Methylbiphenyl

: 6919-61-5
N-methoxy-N-methylbenzamide

: 27644-00-4
2-([1,1'-biphenyl]-4-yl)-1-phenylethanone

Guidance literature:: 4-Methylbiphenyl; With cesium fluoride; lithium hexamethyldisilazane; at 110 ℃; for 4h; Inert atmosphere; Sealed tube;

N-methoxy-N-methylbenzamide; at 50 ℃; for 4h; Inert atmosphere; Sealed tube;
DOI:10.1021/acs.joc.1c02446