32361-73-2

Usage

Uses

Used in Pharmaceutical Industry:
Ethanone, 1-[4-(methylsulfinyl)phenyl]is utilized as an intermediate in the synthesis of various pharmaceuticals due to its reactive functional groups and compatibility with a range of chemical reactions. Its presence in drug formulations can contribute to the development of new therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical sector, Ethanone, 1-[4-(methylsulfinyl)phenyl]- serves as a key component in the production of pesticides and other crop protection agents, leveraging its chemical properties to enhance the effectiveness of these products.
Used in Perfume and Fragrance Industry:
Ethanone, 1-[4-(methylsulfinyl)phenyl]is employed as a scent ingredient in perfumes and fragrances, capitalizing on its strong odor to create distinctive and long-lasting scents for a variety of products.
Used as a Solvent:
Across various industries, Ethanone, 1-[4-(methylsulfinyl)phenyl]- functions as a solvent, facilitating the dissolution of other substances and enabling a range of chemical processes and reactions.
Used in Medicinal Chemistry:
Due to its unique chemical properties, Ethanone, 1-[4-(methylsulfinyl)phenyl]has potential applications in medicinal chemistry, where it may be used in the development of novel drugs and therapeutic agents.

Upstream product

• 1778-09-2 4-(Methylthio)acetophenone 
• 99-92-3 p-aminobenzophenone 
• 67-68-5 dimethyl sulfoxide 
• 3446-89-7 4-(Methylthio)benzaldehyde 
• 144-86-5 N-chloro-4-methylbenzenesulfonamide 

Downstream Products

• 126937-17-5 Acetic acid [1-(4-methanesulfinyl-phenyl)-eth-(E)-ylidene]-hydrazide 
• 1330184-65-0 N-[(4-acetylphenyl)(methyl)(oxo)-λ⁶-sulfanylidene]cyanamide 
• 92017-04-4 (4-acetyl-phenylsulfanyl)-acetic acid methyl ester 
• 1620443-54-0 (4-acetylphenyl)(imino)(methyl)-λ⁶-sulfanone 
• 1778-09-2 4-(Methylthio)acetophenone 
• 10297-73-1 4-(methanesulfonyl)acetophenone 

Relevant academic research and scientific papers

The sulfoxidation reaction catalyzed by CoBr2 complexes, under the magnifying glass of green parameters

Different cobalt (II) and nickel (II) species were used as catalysts in sulfoxidation reactions giving excellent yields and high chemoselectivity. Among the cobalt (II) species, both γ-cyclodextrin complexes synthesized in ethyl acetate or dichloromethane solvents were very good catalysts, while γCDNiBr2 synthesized in ethyl acetate was the best of Ni (II) species. Sulfoxidation takes place with high chemoselectivity in the presence of other groups such as aldehyde. Good results were obtained when these reactions were analyzed using green chemistry metrics. Techniques as FT-IR, UV–vis Diffuse Reflectance, colorimetry, TGA, flame atomic absorption, potentiometric halide titration, and elemental analysis were used to characterize novel complexes. The change of solvent in the synthesis of complexes produces positive effects in holistic green metrics.

Mechanism of Oxidation of Organic Sulphides by Oxo(salen)manganese(V) Complexes

The kinetics of oxygen atom transfer from several cationic oxo(salen)manganese(V) complexes to organic sulphides have been studied spectrophotometrically in acetonitrile at 25 deg C.The reaction follows an o

Borate-catalyzed reactions of hydrogen peroxide: Kinetics and mechanism of the oxidation of organic sulfides by peroxoborates

The kinetics of the oxidation of substituted phenyl methyl sulfides by hydrogen peroxide in borate/boric acid buffers were investigated as a function of pH, total peroxide concentration, and total boron concentration. Second-order rate constants at 25°C f

Effect of added donor ligands on the selective oxygenation of organic sulfides by oxo(salen)chromium(V) complexes

Oxo(salen)chromium(V) complexes, [(salen)CrV{double bond, long}O]+, oxidize organic sulfides selectively to sulfoxides in high yield. This oxygenation reaction is catalyzed by ligand oxides (LO's), pyridine N-oxide, 4-picoline N-oxid

An efficient and selective photocatalytic system for the oxidation of sulfides to sulfoxides

A heterogenous nation membrane containing lead ruthenate pyrochlore (Pyc) and [Ru(bpy)3]2+ (designated as | NPyc-Ru(bpy)|) photochemically catalyzes the selective oxidation of organic sulfide to sulfoxide in the presence o

Mechanism of selective oxidation of organic sulfides with oxo(salen)chromium(V) complexes

The selective oxidation of organic sulfides to sulfoxides by oxo(salen)chromium(V) complexes in acetonitrile is overall second-order, first-order each in the oxidant and the substrate. The rate constant, k2, values of several para-substituted p

Synergistic cooperative effect of CF3SO2Na and bis(2-butoxyethyl)ether towards selective oxygenation of sulfides with molecular oxygen under visible-light irradiation

A safe, practical and eco-friendly method for the switchable synthesis of sulfoxides and sulfones through visible-light-initiated oxygenation of sulfides at ambient temperature under transition-metal-, additives-free and minimal solvent conditions. The synergistic catalytic efforts between CF3SO2Na and 2-butoxyethyl ether represents the key promoting factor for the reaction. This journal is

Organocatalytic sulfoxidation

Treatment of a sulfide with a catalytic amount of a 1,3-diketone in the presence of silica sulfuric acid as a co-catalyst and hydrogen peroxide (50% aq) as the stoichiometric oxidant leads to the corresponding sulfoxide product. The reaction is effective for diaryl, aryl-alkyl and dialkyl sulfides and is tolerant of oxidisable and acid sensitive functional groups. Investigations have shown that the tris-peroxide 2, formed on reaction of pentane-2,4-dione with hydrogen peroxide under acidic reaction conditions, can oxidise two equivalents of sulfide using the exocyclic peroxide groups whereas the endocyclic peroxide remains intact. Calculations provide a mechanism consistent with experimental observations and suggest the reaction proceeds via an initial acid catalysed ring opening of a protonated tris-peroxide prior to oxygen transfer to a sulfur nucleophile.

Electrochemical oxygenation of sulfides with molecular oxygen or water: Switchable preparation of sulfoxides and sulfones

A practical and eco-friendly method for the controllable aerobic oxygenation of sulfides by electrochemical catalysis was developed. The switchable preparation of sulfoxides and sulfones was effectively controlled by reaction time, in which both molecular oxygen and water can be used as the oxygen source under catalyst and external oxidant-free conditions. The electrochemical protocol features a broad substrate scope and excellent site selectivity and is successfully applied to the modification of some sulfide-containing pharmaceuticals and their derivatives. This journal is

Sulfoxide and Sulfone Synthesis via Electrochemical Oxidation of Sulfides

The oxidation of diaryl sulfides and aryl alkyl sulfides to the corresponding sulfoxides and sulfones under electrochemical conditions is reported. Sulfoxides are selectively obtained in good yield under a constant current of 5 mA for 10 h in DMF, while sulfones are formed as the major product under a constant current of 10 or 20 mA for 10 h in MeOH. The oxygen of both the sulfoxide and sulfone function is derived from water.