38922-74-6

Basic information

• Product Name: 2-(4-CHLORO-PHENYL)-IMIDAZO[1,2-A]PYRIDINE
• Synonyms: BUTTPARK 7\05-92;2-(4-CHLORO-PHENYL)-IMIDAZO[1,2-A]PYRIDINE
• CAS NO: 38922-74-6
• Molecular Formula: C₁₃H₉ClN₂
• Molecular Weight: 228.68
• Mol File: 38922-74-6.mol
• Article Data: 97

Chemical Properties

• Melting Point: 208 °C
• Appearance: /
• Density: 1.26±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 6.47±0.50(Predicted)
• CAS DataBase Reference: 2-(4-CHLORO-PHENYL)-IMIDAZO[1,2-A]PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-CHLORO-PHENYL)-IMIDAZO[1,2-A]PYRIDINE(38922-74-6)
• EPA Substance Registry System: 2-(4-CHLORO-PHENYL)-IMIDAZO[1,2-A]PYRIDINE(38922-74-6)

Safety Data

• Hazardous Substances Data: 38922-74-6(Hazardous Substances Data)

Usage

General Description

2-(4-Chloro-phenyl)-imidazo[1,2-a]pyridine is a chemical compound with the molecular formula C12H8ClN3. It is a heterocyclic compound with an imidazo-pyridine structure, which makes it useful in pharmaceutical research as a potential drug candidate. The presence of the chloro-phenyl group suggests that it may have biological activity, potentially making it useful in the development of new drugs. 2-(4-CHLORO-PHENYL)-IMIDAZO[1,2-A]PYRIDINE may have diverse applications as it can be involved in the synthesis of various pharmaceuticals and agrochemicals. Furthermore, it has the potential to be used as a building block in organic chemistry for the preparation of more complex molecules.

Upstream product

• 504-29-0 2-aminopyridine 
• 536-38-9 4-chlorobenzoylmethyl bromide 
• 131947-29-0 2-(4-chlorophenyl)-3-chloroimidazo<1,2-a>pyridine 
• 104-88-1 4-chlorobenzaldehyde 
• 305832-50-2 2-(4'-chlorophenyl)-3-nitrosoimidazo[1,2-a]pyridine 
• 25917-49-1 1-(4-chlorophenyl)-2-(p-tolylsulfonyloxy)ethanone 
• 123466-28-4 [(4-chlorophenyl)ethynyl](phenyl)iodonium tosylate 
• 99-91-2 para-chloroacetophenone 
• 3282-33-5 1-(4-chlorophenyl)-2-diazoethanone 
• 26031-66-3 1-(2-(4-chlorophenyl)-2-oxoethyl)pyridinium bromide 
• 23135-16-2 1,2-dibromo-1-(4-chlorophenyl)ethane 
• 110-86-1 pyridine 
• 53896-48-3 2-iodo-4'-chloroacetophenone 
• 1956-39-4 4-chloroacetophenone oxime 

Downstream Products

• 131947-29-0 2-(4-chlorophenyl)-3-chloroimidazo<1,2-a>pyridine 
• 349482-09-3 2-chloro-1-[2-(4-chloro-phenyl)-imidazo[1,2-a]pyridin-3-yl]-2,2-difluoro-ethanone 
• 305832-50-2 2-(4'-chlorophenyl)-3-nitrosoimidazo[1,2-a]pyridine 
• 338415-39-7 1-(2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)-N,N-dimethylmethanamine 
• 82622-54-6 2-(2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)-N,N-dimethylacetamide 
• 17744-99-9 2-(2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)acetonitrile 
• 21801-83-2 2-[2-(4-chloro-phenyl)-imidazo[1,2-a]pyridin-3-yl]-acetamide 
• 17745-06-1 [2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl]acetic acid 
• 158958-76-0 3-bromo-2-(4'-chlorophenyl)imidazo[1,2-a]pyridine 
• 1310492-82-0 2-(4-chlorophenyl)-3-(phenylthio)-imidazo[1,2-a]pyridine 
• 1360127-61-2 N-((2-(4-chlorophenyl)-imidazo[1,2-a]pyridin-3-yl)(3-nitrophenyl)methyl)acetamide 
• 1357622-10-6 (2E)-3-(2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)-1-(4-methylsulfonylphenyl)prop-2-en-1-one 
• 1357622-11-7 (2E)-3-(2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)-1-(3-fluorophenyl)prop-2-en-1-one 
• 1357622-12-8 (2E)-3-(2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)-1-(3-nitrophenyl)prop-2-en-1-one 

Relevant articles and documents

Solvent and catalyst-free synthesis of imidazo[1,2-a]pyridines by grindstone chemistry

The present work describes the solvent and catalyst-free synthesis of imidazo[1,2-a]pyridines in excellent to nearly quantitative yields from 2-aminopyridines and a wide variety of ω-bromomethylketones using a grindstone procedure at 25°C to 30°C for 3 to

Metal-free, Tf2NH-catalyzed 1, 6-conjugate addition of imidazopyridine to para-quinone methides: Easy access to C3-functionalized triarylmethane imidazopyridine

An inexpensive and commercially available Tf2NH-catalyzed 1,6-conjugate addition of imidazopyridine (IMPY) heterocycles to para-quinone methides (p-QMs) is reported. The present transformation provides a diverse class of C3-functionalized triarylmethanes heterocyclic derivatives of imidazopyridine. These metal-free transformations provided a very broad substrate scope of conjugate addition product with a high yield up to 97% within a short duration.

Synthetic method of imidazopyridine compounds

The invention provides a novel method for synthesizing imidazopyridine compounds. According to the invention, aminopyridine compounds and sulfur ylide are used as original reaction substrates, iron phthalocyanine (FeIIPc) is used as a catalyst, and a series of the imidazopyridine compounds are obtained under the condition that the advantages of mildness, greenness, high efficiency, wide substrateuniversality and the like are achieved.