methyl 4-(1-methoxy-1-oxopropan-2-yl)benzoate

Base Information

Chemical Name:methyl 4-(1-methoxy-1-oxopropan-2-yl)benzoate
CAS No.:77959-48-9
Molecular Formula:C12H14O4
Molecular Weight:222.241
Hs Code.:

Synonyms:

Suppliers and Price of methyl 4-(1-methoxy-1-oxopropan-2-yl)benzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 4-(1-methoxy-1-oxopropan-2-yl)benzoate

Chemical Property:

Vapor Pressure:0.000958mmHg at 25°C
Boiling Point:303°Cat760mmHg
Flash Point:145.7°C
Density:1.125g/cm³

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of methyl 4-(1-methoxy-1-oxopropan-2-yl)benzoate

There total 16 articles about methyl 4-(1-methoxy-1-oxopropan-2-yl)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 554-12-1
propanoic acid methyl ester

: 619-42-1
4-methoxycarbonylphenyl bromide

: 77959-48-9
4-(1-methoxycarbonyl-ethyl)-benzoic acid methyl ester

Guidance literature:: propanoic acid methyl ester; With sodium hexamethyldisilazane; In toluene; at -60 ℃; for 1.5h; Inert atmosphere; Sealed tube;

With zinc(II) chloride; In tetrahydrofuran; toluene; at -35 ℃; for 1h; Inert atmosphere; Sealed tube;

4-methoxycarbonylphenyl bromide; With monophosphine 1,2,3,4,5-pentaphenyl-1'-(di-tert-butylphosphino)ferrocene; bis(dibenzylideneacetone)-palladium⁽⁰⁾; In tetrahydrofuran; toluene; at -15 - 20 ℃; for 4h; Inert atmosphere; Sealed tube;
DOI:10.1021/jo401476f

Reference yield: 86.0%

: 619-42-1
4-methoxycarbonylphenyl bromide

: Methyl 2-<(methoxallyl)oxy>acetate

: 77959-48-9
4-(1-methoxycarbonyl-ethyl)-benzoic acid methyl ester

Guidance literature:: With pyridine; nickel(II) iodide; 4,5-dihydro-2-(pyridin-2-yl)-1H-imidazole; magnesium chloride; zinc; In N,N-dimethyl acetamide; at 20 ℃; for 12h; Reagent/catalyst; Solvent; Catalytic behavior; Schlenk technique; Inert atmosphere;
DOI:10.1021/acs.orglett.9b00174

Reference yield: 75.0%

: 4648-54-8
trimethylsilylazide

: 1076-96-6
methyl 4-vinylbenzoate

: 35733-58-5
tetra(n-butyl)ammonium formate

: 77959-48-9
4-(1-methoxycarbonyl-ethyl)-benzoic acid methyl ester

Guidance literature:: methyl 4-vinylbenzoate; tetra(n-butyl)ammonium formate; With C₃₈H₅₅F₃GeO₃P₂PdS; In N,N-dimethyl-formamide; at 80 ℃; for 6h; Inert atmosphere; Green chemistry;

trimethylsilylazide; In methanol; diethyl ether; at 0 ℃; for 0.5h; regioselective reaction; Inert atmosphere; Green chemistry;
DOI:10.1039/c7cc01377a