2,6-Diethoxyisonicotinic acid

Base Information

• Chemical Name: 2,6-Diethoxyisonicotinic acid
• CAS No.: 5397-75-1
• Molecular Formula: C10H13 N O4
• Molecular Weight: 211.218
• Hs Code.: 2933399090
• Mol file: 5397-75-1.mol

Synonyms:Isonicotinic acid, 2,6-diethoxy- (6CI,7CI); NSC 4259

Chemical Property of 2,6-Diethoxyisonicotinic acid

Chemical Property:

• Vapor Pressure: 3.37E-07mmHg at 25°C
• Boiling Point: 402.4°Cat760mmHg
• Flash Point: 197.2°C
• PSA: 68.65000
• Density: 1.198g/cm³
• LogP: 1.57720
• Storage Temp.: 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

2,6-diethoxyisonicotinicacid 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,6-Diethoxyisonicotinic acid

There total 2 articles about 2,6-Diethoxyisonicotinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

ethanol (64-17-5) + 2,6-dichloropyridine-4-carboxylic acid (5398-44-7) → 2,6-diethoxyisonicotinic acid (5397-75-1)

Guidance literature:

With sodium; at 130 ℃; for 18h;

Reference yield:

sodium ethanolate (141-52-6) + 2,6-dichloropyridine-4-carboxylic acid (5398-44-7) → 2,6-diethoxyisonicotinic acid (5397-75-1)

Guidance literature:

at 130 - 140 ℃;

DOI:10.1002/hlca.19470300208

upstream raw materials:

sodium ethanolate

2,6-dichloropyridine-4-carboxylic acid

ethanol

Refernces