Cyclohexyl 4-[[5-[3-(trifluoromethyl)phenyl]furan-2-carbonyl]amino]benzoate

Base Information

• Chemical Name: Cyclohexyl 4-[[5-[3-(trifluoromethyl)phenyl]furan-2-carbonyl]amino]benzoate
• CAS No.: 7062-04-6
• Molecular Formula: C25H22F3NO4
• Molecular Weight: 206.244
• DSSTox Substance ID: DTXSID60414149
• Mol file: 7062-04-6.mol

Synonyms:7062-04-6;Cyclohexyl 4-[[5-[3-(trifluoromethyl)phenyl]furan-2-carbonyl]amino]benzoate;DTXSID60414149;AKOS002791668

Chemical Property of Cyclohexyl 4-[[5-[3-(trifluoromethyl)phenyl]furan-2-carbonyl]amino]benzoate

Chemical Property:

• Vapor Pressure: 1.52E-10mmHg at 25°C
• Boiling Point: 510.7°Cat760mmHg
• Flash Point: 262.6°C
• Density: 1.33g/cm³
• XLogP3: 6.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 6
• Exact Mass: 457.15009267
• Heavy Atom Count: 33
• Complexity: 671

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1CCC(CC1)OC(=O)C2=CC=C(C=C2)NC(=O)C3=CC=C(O3)C4=CC(=CC=C4)C(F)(F)F

Technology Process of Cyclohexyl 4-[[5-[3-(trifluoromethyl)phenyl]furan-2-carbonyl]amino]benzoate

There total 2 articles about Cyclohexyl 4-[[5-[3-(trifluoromethyl)phenyl]furan-2-carbonyl]amino]benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(1-buten-1-yl)piperidine (7182-10-7) + para-methoxyphenyldiazonium chloride (4346-59-2) → 2-(4-methoxy-phenylhydrazono)-butyraldehyde (7062-04-6)

Guidance literature:

DOI:10.1021/ja01602a033

Reference yield:

N-(1-buten-1-yl)piperidine (7182-10-7) + 4-methoxy-aniline (104-94-9) → 2-(4-methoxy-phenylhydrazono)-butyraldehyde (7062-04-6)

Guidance literature:

Multistep reaction; (i) aq. HCl, NaNO₂, (ii) /BRN= 2069/;

Reference yield:

2-(4-methoxy-phenylhydrazono)-butyraldehyde (7062-04-6) → 2-aminobutanol (96-20-8,13054-87-0)

Guidance literature:

Multistep reaction; (i) aq. NaBH₄, EtOH, (ii) H₂, Ni, MeOH;

upstream raw materials:

N-(1-buten-1-yl)piperidine

para-methoxyphenyldiazonium chloride

4-methoxy-aniline

Downstream raw materials:

2-aminobutanol