4,6-difluoro-1H-imidazo[4,5-c]pyridine

Base Information

Chemical Name:4,6-difluoro-1H-imidazo[4,5-c]pyridine
CAS No.:60186-30-3
Molecular Formula:C6H3F2N3
Molecular Weight:155.107
Hs Code.:
NSC Number:264049
DSSTox Substance ID:DTXSID60418420
Wikidata:Q82228946

Synonyms:4,6-difluoro-1H-imidazo[4,5-c]pyridine;60186-30-3;3,5-difluoro-4,7,9-triazabicyclo[4.3.0]nona-1,3,5,7-tetraene;NSC264049;SCHEMBL6313592;DTXSID60418420;MFCD20617367;NSC-264049;AS-79078;4,6-difluoro-3H-Imidazo[4,5-c]pyridine;3h-imidazo[4,5-c]pyridine,4,6-difluoro-;CS-0310439

Suppliers and Price of 4,6-difluoro-1H-imidazo[4,5-c]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 8 raw suppliers

Chemical Property of 4,6-difluoro-1H-imidazo[4,5-c]pyridine

Chemical Property:

Vapor Pressure:6.97E-08mmHg at 25°C
Boiling Point:450.5°Cat760mmHg
Flash Point:226.3°C
Density:1.603g/cm³
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:155.02950343
Heavy Atom Count:11
Complexity:155

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C2C(=C(N=C1F)F)N=CN2

Technology Process of 4,6-difluoro-1H-imidazo[4,5-c]pyridine

There total 11 articles about 4,6-difluoro-1H-imidazo[4,5-c]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 14036-06-7
diethoxymethyl acetate

: 60186-25-6
3,4-diamino-2,6-difluoropyridine

: 60186-30-3
4,6-difluoro-1H-imidazo[4,5-c]pyridine

: 405231-22-3
1-[(1-acetyloxy-1-ethoxy)methyl]-4,6-difluoroimidazo[4,5-c]pyridine

Guidance literature:: DOI:10.1081/NCN-100108327

Reference yield: 85.0%

: 14036-06-7
diethoxymethyl acetate

: 60186-25-6
3,4-diamino-2,6-difluoropyridine

: 60186-30-3
4,6-difluoro-1H-imidazo[4,5-c]pyridine

Guidance literature:: at 100 ℃; for 1h;

Reference yield:

: 63489-58-7
4-amino-2,6-difluoropyridine

: 60186-30-3
4,6-difluoro-1H-imidazo[4,5-c]pyridine

Guidance literature:: Multi-step reaction with 4 steps

1: 76 percent / conc. H₂SO₄; KNO₃ / 0 - 20 °C

2: 89 percent / conc. H₂SO₄ / 20 °C

3: 92 percent / H₂ / Raney Ni / ethanol

With sulfuric acid; hydrogen; potassium nitrate; nickel; In ethanol;
DOI:10.1081/NCN-100108327