(4-Benzylaminophenyl)acetic acid

Base Information

Chemical Name:(4-Benzylaminophenyl)acetic acid
CAS No.:39718-80-4
Molecular Formula:C15H15NO2
Molecular Weight:241.29
Hs Code.:
DSSTox Substance ID:DTXSID00192797
Nikkaji Number:J85.191D
Wikidata:Q83065453
ChEMBL ID:CHEMBL237618
Mol file:39718-80-4.mol

Synonyms:(4-Benzylaminophenyl)acetic acid;39718-80-4;2-[4-(benzylamino)phenyl]acetic acid;ACETIC ACID, 2-(p-(BENZYLAMINO)PHENYL)-;BRN 2376457;Acide benzylamino-4 phenylacetique [French];Acide benzylamino-4 phenylacetique;4-14-00-01314 (Beilstein Handbook Reference);2-(4-(benzylamino)phenyl)acetic acid;Oprea1_309277;CHEMBL237618;SCHEMBL5447986;DTXSID00192797;2-[p-(Benzylamino)phenyl]acetic acid;AKOS022228672;Benzeneacetic acid, 4-[(phenylmethyl)amino]-;EN300-651267;SR-01000579765;SR-01000579765-1;Z2049903594

Suppliers and Price of (4-Benzylaminophenyl)acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of (4-Benzylaminophenyl)acetic acid

Chemical Property:

Vapor Pressure:3.08E-08mmHg at 25°C
Boiling Point:432.2°Cat760mmHg
Flash Point:215.2°C
Density:1.224g/cm³
XLogP3:2.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:241.110278721
Heavy Atom Count:18
Complexity:253

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CNC2=CC=C(C=C2)CC(=O)O

Technology Process of (4-Benzylaminophenyl)acetic acid

There total 9 articles about (4-Benzylaminophenyl)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 1197-55-3
4-aminophenylacetic acid

: 100-52-7
benzaldehyde

: 39718-80-4
4-(benzylamino)phenylacetic acid

Guidance literature:: With diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; thiourea; In toluene; at 70 ℃; for 24h;
DOI:10.1055/s-2006-939052

Reference yield: 52.0%

: 57960-76-6
ethyl 2-(4-(benzylamino)phenyl)acetate

: 39718-80-4
4-(benzylamino)phenylacetic acid

Guidance literature:: ethyl 2-(4-(benzylamino)phenyl)acetate; With potassium hydroxide; In methanol; water; at 20 ℃; for 8h; Inert atmosphere;

With hydrogenchloride; water; In methanol;
DOI:10.1039/c3cc44438d

Reference yield:

: 14062-25-0
Ethyl 4-bromophenylacetate

: 39718-80-4
4-(benzylamino)phenylacetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: palladium diacetate; XPhos; caesium carbonate / toluene / 12 h / 100 °C / Inert atmosphere

2: potassium hydroxide / methanol; water / 8 h / 20 °C / Inert atmosphere

With palladium diacetate; caesium carbonate; potassium hydroxide; XPhos; In methanol; water; toluene;
DOI:10.1039/c3cc44438d