N,4-dimethylbenzenesulfonohydrazide

Base Information

• Chemical Name: N,4-dimethylbenzenesulfonohydrazide
• CAS No.: 22547-51-9
• Molecular Formula: C8H12 N2 O2 S
• Molecular Weight: 200.261
• NSC Number: 132041
• DSSTox Substance ID: DTXSID70299681
• Nikkaji Number: J1.670.494F
• Wikidata: Q82042191
• Mol file: 22547-51-9.mol

Synonyms:N,4-dimethylbenzenesulfonohydrazide;22547-51-9;Benzenesulfonic acid, 4-methyl-, 1-methylhydrazide;NSC132041;SCHEMBL420472;DTXSID70299681;NWHQWDAMGMGFOF-UHFFFAOYSA-N;N,4-dimethyl-benzenesulfonohydrazide;NSC-132041;2-methyl-2-(4-methylphenyl)sulfonyl hydrazine;2-methyl-2-[(4-methylphenyl)sulfonyl] hydrazine

Chemical Property of N,4-dimethylbenzenesulfonohydrazide

Chemical Property:

• Vapor Pressure: 0.000113mmHg at 25°C
• Boiling Point: 336.4°Cat760mmHg
• Flash Point: 157.2°C
• Density: 1.264g/cm³
• XLogP3: 2.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 200.06194880
• Heavy Atom Count: 13
• Complexity: 250

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)S(=O)(=O)N(C)N

Technology Process of N,4-dimethylbenzenesulfonohydrazide

There total 5 articles about N,4-dimethylbenzenesulfonohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

p-toluenesulfonyl chloride (98-59-9) + methylhydrazine (60-34-4) → 1-methyl-1-(4-tolylsulfonyl)hydrazine (22547-51-9)

Guidance literature:

In tetrahydrofuran; at 0 - 5 ℃; for 4h;

DOI:10.1021/jm00159a036

Reference yield: 80.0%

N-methyl-p-toluenesulfonylamide (640-61-9) → 1-methyl-1-(4-tolylsulfonyl)hydrazine (22547-51-9)

Guidance literature:

With potassium tert-butylate; hydroxylamine-O-sulfonic acid; In methanol; isopropyl alcohol; for 0.5h;

DOI:10.1055/s-1983-30383

Reference yield:

C7H9N2O2S(1-)*Li(1+) + methyl iodide (74-88-4) → 1-methyl-1-(4-tolylsulfonyl)hydrazine (22547-51-9)

Guidance literature:

In dimethyl sulfoxide;

DOI:10.1021/ja00737a025

upstream raw materials:

p-toluenesulfonyl chloride

methylhydrazine

methyl iodide

N-methyl-p-toluenesulfonylamide

Downstream raw materials:

Methylen-N-methyl-N-tosylhydrazon

N-methyl-N-nitrosotoluene-p-sulfonamide

N-methyl-N'-benzylidene-4-methylbenzenesulfonohydrazide

isobutyraldehyde methyl-(toluene-4-sulfonyl)-hydrazone