2,3,4,5-tetraphenylfuran

Base Information

• Chemical Name: 2,3,4,5-tetraphenylfuran
• CAS No.: 1056-77-5
• Molecular Formula: C28H20O
• Molecular Weight: 372.466
• Mol file: 1056-77-5.mol

Synonyms:2,3,4,5-Tetraphenylfuran;Furan, tetraphenyl-;Tetraphenylfuran;

Chemical Property of 2,3,4,5-tetraphenylfuran

Chemical Property:

• Vapor Pressure: 4.69E-07mmHg at 25°C
• Melting Point: 175°C
• Refractive Index: 1.618
• Boiling Point: 425.6 °C at 760 mmHg
• Flash Point: 206.9 °C
• PSA: 13.14000
• Density: 1.117 g/cm³
• LogP: 7.94760

Purity/Quality:

98%,99%, ^*data from raw suppliers

TETRAPHENYLFURAN Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,3,4,5-tetraphenylfuran

There total 89 articles about 2,3,4,5-tetraphenylfuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

2,5-bis(methylthio)-3,4-diphenylfuran + phenylmagnesium bromide (100-58-3) → 2,3,4,5-tetraphenylfuran (1056-77-5)

Guidance literature:

With NiCl₂(PPh₃)(IPr); In toluene; at 100 ℃; Inert atmosphere;

DOI:10.1021/acs.orglett.1c04242

Reference yield: 95.0%

diphenyl acetylene (501-65-5) → 2,3,4,5-tetraphenylfuran (1056-77-5)

Guidance literature:

With oxygen; copper diacetate; palladium diacetate; acetic acid; at 100 ℃; for 12h; under 757.576 Torr; Solvent; Reagent/catalyst; Green chemistry;

DOI:10.1002/cjoc.201400386

Reference yield: 89.0%

phenyl benzyl ketone (451-40-1) → 2,3,4,5-tetraphenylfuran (1056-77-5)

Guidance literature:

phenyl benzyl ketone; With silver fluoride; In 5,5-dimethyl-1,3-cyclohexadiene; at 140 ℃; for 6h;

With toluene-4-sulfonic acid; In 5,5-dimethyl-1,3-cyclohexadiene; for 3h; Solvent; Reagent/catalyst; Temperature;

DOI:10.1002/chem.201501410

upstream raw materials:

phenyl benzyl ketone

1,2,3,4-tetraphenylbutane-1,4-dione

1,4-diphenyl-but-2-ene-1,4-dione

1-phenyl-1,2-dibenzoylethylene

Downstream raw materials:

Octaphenyl-1:2,9:10-dibenzo<2.2>pyracylophan-1,9-dien

cis-dibenzoylstilbene oxide

1,3,8-trimethyl-6-phenylpteridine-2,4,7-trione

1,2,3,4-tetraphenyldibenzo<2.2>paracyclophane

Refernces

• 1、 Wu, Yong,Huang, Zhiyuan,Luo, Yi,Liu, Dong,Deng, Yi,Yi, Hong,Lee, Jyh-Fu,Pao, Chih-Wen,Chen, Jeng-Lung,Lei, Aiwen. "X-ray Absorption and Electron Paramagnetic Resonance Guided Discovery of the Cu-Catalyzed Synthesis of Multiaryl-Substituted Furans from Aryl Styrene and Ketones Using DMSO as the Oxidant". . p. 2330 - 2333. Retrieved 2017.
• 2、 Halpern et al.. "-". . p. 149,150, 151. Retrieved 1966.
• 3、 Sheehan,Wilson. "-". . p. 5277,5280. Retrieved 1964.
• 4、 Kharitonov, Vladimir B.,Loginov, Dmitry A.,Muratov, Dmitry V.,Nelyubina, Yulia V.. "Formation of a Naphthalene Framework by Rhodium(III)-Catalyzed Double C-H Functionalization of Arenes with Alkynes: Impact of a Supporting Ligand and an Acid Additive". supporting information. . Retrieved 2022/03/01.