2-[(Tetrahydrofurfuryl)oxy]ethanol

Base Information

• Chemical Name: 2-[(Tetrahydrofurfuryl)oxy]ethanol
• CAS No.: 5831-59-4
• Molecular Formula: C7H14 O3
• Molecular Weight: 146.186
• European Community (EC) Number: 227-407-8
• DSSTox Substance ID: DTXSID40923709
• Nikkaji Number: J218.084G
• Mol file: 5831-59-4.mol

Synonyms:chromophore EL;glycofurol;tetraglycol;tetrahydrofurfuryl alcohol polyethylene glycol ether

Chemical Property of 2-[(Tetrahydrofurfuryl)oxy]ethanol

Chemical Property:

• Boiling Point: 256.2°Cat760mmHg
• Flash Point: 108.7°C
• PSA: 38.69000
• Density: 1.061g/cm³
• LogP: 0.17430
• XLogP3: -0.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 146.094294304
• Heavy Atom Count: 10
• Complexity: 84.9

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-[(oxolan-2-yl)methoxy]ethan-1-ol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC(OC1)COCCO
• Uses: 2-[(oxolan-2-yl)methoxy]ethan-1-ol (cas# 5831-59-4) is used in the preparation of 2-?[(heterocyclyloxy)?phenoxy]?propanoates as herbicides. It is also used in the preparation of radiopaque polymers as liquid emoblics in therapetuci emboisation, and in preparation of purine derivatives which induce human interferon α.

Technology Process of 2-[(Tetrahydrofurfuryl)oxy]ethanol

There total 3 articles about 2-[(Tetrahydrofurfuryl)oxy]ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(Tetrahydrofuran-2-ylmethoxy)acetic Ethyl Ester (836657-20-6) → 2-tetrahydrofurfuryloxy-ethanol (5831-59-4)

Guidance literature:

(Tetrahydrofuran-2-ylmethoxy)acetic Ethyl Ester; With lithium aluminium tetrahydride; In diethyl ether; at 0 - 20 ℃; for 19.5h; Inert atmosphere;

With water; sodium hydroxide; Cooling with ice;

Reference yield:

oxirane (75-21-8,99932-75-9) + Tetrahydrofurfuryl alcohol (97-99-4) → 2-tetrahydrofurfuryloxy-ethanol (5831-59-4)

Guidance literature:

With sodium hydroxide;

Reference yield:

→ 2-tetrahydrofurfuryloxy-ethanol (5831-59-4)

Guidance literature:

Aus Natrium-tetrahydrofurfurylat u. 2-Chlor-aethanol in Toluol ;

upstream raw materials:

oxirane

Tetrahydrofurfuryl alcohol

(Tetrahydrofuran-2-ylmethoxy)acetic Ethyl Ester

Downstream raw materials:

2-{[(2-bromoethyl)oxy]methyl}tetrahydrofuran

Refernces