2-Methyl-3,3-diphenylpropanenitrile

Base Information

Chemical Name:2-Methyl-3,3-diphenylpropanenitrile
CAS No.:92962-30-6
Molecular Formula:C16H15N
Molecular Weight:221.297
Hs Code.:
NSC Number:120401
DSSTox Substance ID:DTXSID60298047

Synonyms:2-methyl-3,3-diphenylpropanenitrile;92962-30-6;NSC120401;DTXSID60298047;NSC-120401;EN300-1861385

Suppliers and Price of 2-Methyl-3,3-diphenylpropanenitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 2-Methyl-3,3-diphenylpropanenitrile

Chemical Property:

Vapor Pressure:7.44E-06mmHg at 25°C
Boiling Point:376.1°Cat760mmHg
Flash Point:194.8°C
Density:1.039g/cm³
XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:221.120449483
Heavy Atom Count:17
Complexity:245

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C#N)C(C1=CC=CC=C1)C2=CC=CC=C2

Technology Process of 2-Methyl-3,3-diphenylpropanenitrile

There total 1 articles about 2-Methyl-3,3-diphenylpropanenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 2286-54-6
3,3-diphenyl-propionitrile

: 74-88-4
methyl iodide

: 92962-30-6
2-methyl-3,3-diphenylpropanenitrile

Guidance literature:: 3,3-diphenyl-propionitrile; With n-butyllithium; diisopropylamine; In tetrahydrofuran; hexane; at -78 ℃; for 1h; Inert atmosphere;

methyl iodide; In tetrahydrofuran; hexane; at -78 ℃; for 1h; Inert atmosphere;
DOI:10.1021/ja312141b

Reference yield: 88.0%

: 92962-30-6
2-methyl-3,3-diphenylpropanenitrile

: 18162-48-6
tert-butyldimethylsilyl chloride

: 1421692-14-9
1-tert-butyl-1,1-dimethyl-N-(2-methyl-3,3-diphenylprop-1-en-1-ylidene)silanamine

Guidance literature:: 2-methyl-3,3-diphenylpropanenitrile; With n-butyllithium; diisopropylamine; In tetrahydrofuran; hexane; at -78 ℃; for 0.0833333h; Inert atmosphere;

tert-butyldimethylsilyl chloride; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 12h; Inert atmosphere;
DOI:10.1021/ja312141b

Reference yield:

: 92962-30-6
2-methyl-3,3-diphenylpropanenitrile

: 62907-42-0
(S)-2-methyl-3,3-diphenylpropanenitrile

: 28098-85-3
(R)-2-methyl-3,3-diphenylpropanenitrile

Guidance literature:: Multi-step reaction with 2 steps

1.1: diisopropylamine; n-butyllithium / tetrahydrofuran; hexane / 0.08 h / -78 °C / Inert atmosphere

1.2: 12 h / -78 - 20 °C / Inert atmosphere

2.1: (S)-3,3'-bis(2,4,6-tri-iso-propylphenyl)-1,1'-binaphthyl-2,2'-diyl hydrogenphosphate / methanol; toluene; pentane / 12 h / -78 - 20 °C

With n-butyllithium; (S)-3,3'-bis(2,4,6-tri-iso-propylphenyl)-1,1'-binaphthyl-2,2'-diyl hydrogenphosphate; diisopropylamine; In tetrahydrofuran; methanol; hexane; toluene; pentane;
DOI:10.1021/ja312141b