6-(Dimethylamino)hexylamine

Base Information

• Chemical Name: 6-(Dimethylamino)hexylamine
• CAS No.: 1938-58-5
• Molecular Formula: C8H20 N2
• Molecular Weight: 144.26
• Hs Code.: 2921290000
• European Community (EC) Number: 803-123-5
• NSC Number: 87565
• DSSTox Substance ID: DTXSID90293161
• Nikkaji Number: J3.570.354C
• Wikidata: Q72468986
• Mol file: 1938-58-5.mol

Synonyms:6-(Dimethylamino)hexylamine;1938-58-5;N1,N1-Dimethylhexane-1,6-diamine;n,n-dimethylhexane-1,6-diamine;(6-aminohexyl)dimethylamine;N',N'-dimethylhexane-1,6-diamine;MFCD00047980;N1,N1-Dimethyl-hexane-1,6-diamine;1,6-Hexanediamine, N,N-dimethyl-;NSC87565;dimethylaminohexylamine;6-dimethylamino-hexylamine;6-(dimethylamino)-hexylamine;SCHEMBL421181;n,n-dimethylhexamethylenediamine;n,n-dimethyl-1,6-hexanediamine;DTXSID90293161;N,N-dimethyl-hexane-1,6-diamine;ZUXUNWLVIWKEHB-UHFFFAOYSA-N;BAA93858;BBL104023;NSC-87565;STL557836;AKOS000262488;CS-0214706;FT-0620813;F87831;EN300-1870758;A888652;J-012552

Chemical Property of 6-(Dimethylamino)hexylamine

Chemical Property:

• Vapor Pressure: 0.341mmHg at 25°C
• Boiling Point: 199.4°Cat760mmHg
• PKA: 10?+-.0.10(Predicted)
• Flash Point: 74.6°C
• PSA: 29.26000
• Density: 0.841g/cm³
• LogP: 1.76740
• XLogP3: 0.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 6
• Exact Mass: 144.162648646
• Heavy Atom Count: 10
• Complexity: 62.3

Purity/Quality:

98%,99%, ^*data from raw suppliers

6-(Dimethylamino)hexylamine 97% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: C,Xn
• Statements: 34-35-21/22-10
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)CCCCCCN

Technology Process of 6-(Dimethylamino)hexylamine

There total 22 articles about 6-(Dimethylamino)hexylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

6-dimethylaminohexyl azide → N,N-dimethyl-1,6-hexanediamine (1938-58-5)

Guidance literature:

With 5%-palladium/activated carbon; hydrogen; In ethanol; at 20 ℃; for 6h; under 6080.41 Torr; Autoclave;

DOI:10.24820/ark.5550190.p010.321

Reference yield: 69.0%

tert-butyl N-<6-(dimethylamino)hexyl>carbamate (149301-37-1) → N,N-dimethyl-1,6-hexanediamine (1938-58-5)

Guidance literature:

With hydrogenchloride; In ethyl acetate; for 15h; Ambient temperature;

DOI:10.1002/hlca.19930760212

Reference yield:

methanol (67-56-1) + 1,6-Hexanediamine (124-09-4) → N-methyl-hexanediyldiamine (2997-06-0) + N,N'-dimethyl-1,6-hexanediamine (13093-04-4) + N,N-dimethyl-1,6-hexanediamine (1938-58-5)

Guidance literature:

With Cs-P-Si; at 300 ℃; under 61504.9 Torr;

DOI:10.1021/ja048557s

upstream raw materials:

formaldehyd

hexane-1,6-diamine dihydrochloride

6-dimethylaminohexanenitrile

6-Dimethylamino-6-oxohexanoic acid

Downstream raw materials:

N,N,N',N'-tetramethylhexamethylenediamine

3-(2,5-Difluoro-4-methyl-benzyloxy)-5-[3-(6-dimethylamino-hexyl)-ureido]-isothiazole-4-carboxylic acid amide

N-{4-[7-(1H-indol-5-ylamino)-thieno[3,2-b]pyridin-2-yl]-benzyl}-N',N'-dimethyl-hexane-1,6-diamine

Refernces

• 1、 Patel, Dushyant V.,Patel, Nirav R.,Kanhed, Ashish M.,Patel, Sagar P.,Sinha, Anshuman,Kansara, Deep D.,Mecwan, Annie R.,Patel, Sarvangee B.,Upadhyay, Pragnesh N.,Patel, Kishan B.,Shah, Dharti B.,Prajapati, Navnit K.,Murumkar, Prashant R.,Patel, Kirti V.,Yadav, Mange Ram. "Novel Multitarget Directed Triazinoindole Derivatives as Anti-Alzheimer Agents". . p. 3635 - 3661. Retrieved 2019/08/20.
• 2、 Oku, Tomoharu,Arita, Yoshitaka,Tsuneki, Hideaki,Ikariya, Takao. "Continuous chemoselective methylation of functionalized amines and diols with supercritical methanol over solid acid and acid-base bifunctional catalysts". . p. 7368 - 7377. Retrieved 2007/10/03.