3H-Imidazo[4,5-B]pyridin-7-amine

Base Information

• Chemical Name: 3H-Imidazo[4,5-B]pyridin-7-amine
• CAS No.: 6703-44-2
• Molecular Formula: C6H6N4
• Molecular Weight: 134.14
• Hs Code.: 2933990090
• European Community (EC) Number: 843-674-9
• DSSTox Substance ID: DTXSID30397713
• Nikkaji Number: J389.318I
• Wikidata: Q82199275
• ChEMBL ID: CHEMBL579385
• Mol file: 6703-44-2.mol

Synonyms:3H-IMIDAZO[4,5-B]PYRIDIN-7-AMINE;6703-44-2;1H-imidazo[4,5-b]pyridin-7-amine;1-deazaadenine;7-Aminoimidazo[4,5-b]pyridine;CHEMBL579385;SCHEMBL4767690;DTXSID30397713;WVUMWAQTSDFVGS-UHFFFAOYSA-N;MFCD11846336;AKOS006342724;AKOS022184670;AM86122;SB14815;CS-0283623;FT-0728890;EN300-91566;F18031;A858289

Chemical Property of 3H-Imidazo[4,5-B]pyridin-7-amine

Chemical Property:

• Melting Point: 257-259 °C(Solv: methanol (67-56-1); acetonitrile (75-05-8))
• Boiling Point: 199.5±50.0 °C(Predicted)
• PKA: 9.05±0.20(Predicted)
• PSA: 67.59000
• Density: 1.61±0.1 g/cm3(Predicted)
• LogP: 1.12130
• XLogP3: 0.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 134.059246208
• Heavy Atom Count: 10
• Complexity: 127

Purity/Quality:

97% ^*data from raw suppliers

3H-Imidazo[4,5-b]pyridin-7-amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CN=C2C(=C1N)NC=N2

Technology Process of 3H-Imidazo[4,5-B]pyridin-7-amine

There total 9 articles about 3H-Imidazo[4,5-B]pyridin-7-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

7-Amino-3H-imidazo<4,5-b>pyridine 4-N-Oxide (77712-93-7) → 1-Deazaadenine (6703-44-2)

Guidance literature:

With hydrogen;

DOI:10.1002/jhet.5570170824

Reference yield: 61.0%

7-nitro-3H-imidazo<4,5-b>pyridine (109151-82-8) → 1-Deazaadenine (6703-44-2)

Guidance literature:

With hydrogen; In methanol; at 20 ℃; for 6h; under 2585.81 Torr;

DOI:10.1021/jm9006356

Reference yield:

7-nitro-1H-imidazo[4,5-b]pyridine 4-oxide (14432-11-2) → 1-Deazaadenine (6703-44-2)

Guidance literature:

With hydrogen; palladium on activated charcoal; In acetic anhydride; acetic acid; for 6h; under 2280 Torr; Yield given;

DOI:10.1002/jhet.5570170824

upstream raw materials:

pyridine

formaldehyd

copper diacetate

pyridine-2,3,4-triyltriamine; dihydrochloride