1-(7-Nitro-9h-fluoren-2-yl)ethanone

Base Information

• Chemical Name: 1-(7-Nitro-9h-fluoren-2-yl)ethanone
• CAS No.: 34172-49-1
• Molecular Formula: C15H11NO3
• Molecular Weight: 253.25
• NSC Number: 116734
• DSSTox Substance ID: DTXSID20297591
• Wikidata: Q82038768
• Mol file: 34172-49-1.mol

Synonyms:1-(7-nitro-9h-fluoren-2-yl)ethanone;34172-49-1;NSC116734;SCHEMBL9264402;DTXSID20297591;AKOS025402293;AC-7883;NSC-116734

Chemical Property of 1-(7-Nitro-9h-fluoren-2-yl)ethanone

Chemical Property:

• Vapor Pressure: 1.83E-08mmHg at 25°C
• Melting Point: 228 °C
• Refractive Index: 1.655
• Boiling Point: 455 °C at 760 mmHg
• Flash Point: 226.9 °C
• Density: 1.321 g/cm³
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 253.07389321
• Heavy Atom Count: 19
• Complexity: 389

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(=O)C1=CC2=C(C=C1)C3=C(C2)C=C(C=C3)[N+](=O)[O-]

Technology Process of 1-(7-Nitro-9h-fluoren-2-yl)ethanone

There total 4 articles about 1-(7-Nitro-9h-fluoren-2-yl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.7%

2-nitro-9H-fluorene (607-57-8) + acetyl chloride (75-36-5) → 1-(7-nitro-9H-fluorene-2-yl)ethanone (34172-49-1)

Guidance literature:

With aluminum (III) chloride; In nitrobenzene; at 45 - 65 ℃; for 1.5h;

Reference yield:

2-ethylfluorene (1207-20-1) → 1-(7-nitro-9H-fluorene-2-yl)ethanone (34172-49-1)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic acid; HNO₃

2: CrO₃; acetic acid

With chromium(VI) oxide; nitric acid; acetic acid;

DOI:10.1021/ja01637a083

Reference yield:

2-ethyl-7-nitro-fluorene (80382-46-3) → 1-(7-nitro-9H-fluorene-2-yl)ethanone (34172-49-1) + 2-ethyl-7-nitro-fluoren-9-one

Guidance literature:

With chromium(VI) oxide; acetic acid;

DOI:10.1021/ja01637a083

upstream raw materials:

2-ethyl-7-nitro-fluorene

2-nitro-9H-fluorene

acetyl chloride

aluminium trichloride

Downstream raw materials:

7-hydroxy-2-nitrofluorene

2-methoxy-7-nitrofluorene

7-methoxy-N-hydroxy-2-acetamidofluorene

7-acetyl-N-hydroxy-2-acetamidofluorene