Diethyl 1,4-dihydro-2,6-dimethyl-4-propylpyridine-3,5-dicarboxylate

Base Information

Chemical Name:Diethyl 1,4-dihydro-2,6-dimethyl-4-propylpyridine-3,5-dicarboxylate
CAS No.:1156-64-5
Molecular Formula:C16H25 N O4
Molecular Weight:295.379
Hs Code.:2933399090
European Community (EC) Number:214-592-5
DSSTox Substance ID:DTXSID20151144
Nikkaji Number:J203.415H
ChEMBL ID:CHEMBL1098869,CHEMBL3210742
Mol file:1156-64-5.mol

Synonyms:1156-64-5;Diethyl 1,4-dihydro-2,6-dimethyl-4-propylpyridine-3,5-dicarboxylate;diethyl 2,6-dimethyl-4-propyl-1,4-dihydropyridine-3,5-dicarboxylate;CHEMBL1098869;EINECS 214-592-5;C16H25NO4;MLS000109060;Oprea1_026607;SCHEMBL9139821;CHEMBL3210742;DTXSID20151144;HMS2291N08;BDBM50073945;AKOS024368208;SMR000105007;1,4-Dihydro-2,6-dimethyl-4-propyl-3,5-pyridinedicarboxylic acid diethyl ester

Suppliers and Price of Diethyl 1,4-dihydro-2,6-dimethyl-4-propylpyridine-3,5-dicarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 8 raw suppliers

Chemical Property of Diethyl 1,4-dihydro-2,6-dimethyl-4-propylpyridine-3,5-dicarboxylate

Chemical Property:

Vapor Pressure:2.92E-06mmHg at 25°C
Boiling Point:389.1°Cat760mmHg
Flash Point:189.1°C
PSA：64.63000
Density:1.042g/cm³
LogP:3.00890
XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:8
Exact Mass:295.17835828
Heavy Atom Count:21
Complexity:437

Purity/Quality:: 98%,99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCC1C(=C(NC(=C1C(=O)OCC)C)C)C(=O)OCC

Technology Process of Diethyl 1,4-dihydro-2,6-dimethyl-4-propylpyridine-3,5-dicarboxylate

There total 6 articles about Diethyl 1,4-dihydro-2,6-dimethyl-4-propylpyridine-3,5-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 141-97-9
ethyl acetoacetate

: 123-72-8
butyraldehyde

: 1156-64-5
2,6-dimethyl-4-propyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester

Guidance literature:: With ammonium acetate; In water; for 4h; Heating;
DOI:10.1246/bcsj.79.454

Reference yield: 75.0%

: 506-87-6,6721-33-1,10361-29-2
ammonium carbonate

: 141-97-9
ethyl acetoacetate

: 123-72-8
butyraldehyde

: 1156-64-5
2,6-dimethyl-4-propyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester

Guidance literature:: In water; at 80 ℃;
DOI:10.1016/j.ejmech.2015.03.018

Reference yield: 68.0%

: 141-97-9
ethyl acetoacetate

: 626-34-6
ethyl 3-aminobut-2-enoate

: 123-72-8
butyraldehyde

: 1156-64-5
2,6-dimethyl-4-propyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester

Guidance literature:: With tetra(n-butyl)ammonium hydrogensulfate; In ethylene glycol; at 85 ℃; for 4h; Inert atmosphere;
DOI:10.1021/jacs.9b09127