N-[4-(10H-phenothiazin-10-ylsulfonyl)phenyl]acetamide

Base Information

Chemical Name:N-[4-(10H-phenothiazin-10-ylsulfonyl)phenyl]acetamide
CAS No.:34945-70-5
Molecular Formula:C20H16N2O3S2
Molecular Weight:396.491
Hs Code.:
NSC Number:95846
DSSTox Substance ID:DTXSID80956410
Wikidata:Q82936477
Mol file:34945-70-5.mol

Synonyms:N-[4-(10H-phenothiazin-10-ylsulfonyl)phenyl]acetamide;34945-70-5;NSC95846;Oprea1_154268;Oprea1_463147;DTXSID80956410;CCG-17559;NSC-95846;STK072826;AKOS000618274;10-(p-acetamidobenzenesulfonyl)phenothiazine;N-[4-(10H-PHENOTHIAZINE-10-SULFONYL)PHENYL]ACETAMIDE;N-[4-(10H-Phenothiazine-10-sulfonyl)phenyl]ethanimidic acid

Suppliers and Price of N-[4-(10H-phenothiazin-10-ylsulfonyl)phenyl]acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of N-[4-(10H-phenothiazin-10-ylsulfonyl)phenyl]acetamide

Chemical Property:

Density:1.431g/cm³
XLogP3:3.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:396.06023472
Heavy Atom Count:27
Complexity:618

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC1=CC=C(C=C1)S(=O)(=O)N2C3=CC=CC=C3SC4=CC=CC=C42

Technology Process of N-[4-(10H-phenothiazin-10-ylsulfonyl)phenyl]acetamide

There total 6 articles about N-[4-(10H-phenothiazin-10-ylsulfonyl)phenyl]acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.5%

: 58285-39-5
10-(4-amino-benzenesulfonyl)-10H-phenothiazine

: 75-36-5
acetyl chloride

: 34945-70-5
N-[4-(10H-phenothiazine-10-sulfonyl)phenyl]acetamide

Guidance literature:: With triethylamine; In dichloromethane; at -5 ℃; for 0.5h;

Reference yield: 45.0%

: 92-84-2
10H-phenothiazine

: 121-60-8
p-acetylaminobenzenesulfonyl chloride

: 34945-70-5
N-[4-(10H-phenothiazine-10-sulfonyl)phenyl]acetamide

Guidance literature:: With pyridine; at 50 ℃; Inert atmosphere;
DOI:10.1007/s00706-016-1661-6

Reference yield:

: 98-74-8
4-Nitrobenzenesulfonyl chloride

: 34945-70-5
N-[4-(10H-phenothiazine-10-sulfonyl)phenyl]acetamide

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / dichloromethane / 1 h / Cooling with ice

2: hydrogenchloride; tin(II) chloride dihdyrate / ethanol; water / 10 h / 50 °C

3: triethylamine / dichloromethane / 0.5 h / -5 °C

With hydrogenchloride; tin(II) chloride dihdyrate; triethylamine; In ethanol; dichloromethane; water;