Ethyl 3-(2-pyrazinyl)-3-oxopropanoate

Base Information

Chemical Name:Ethyl 3-(2-pyrazinyl)-3-oxopropanoate
CAS No.:62124-77-0
Molecular Formula:C9H10 N2 O3
Molecular Weight:194.19
Hs Code.:2933990090
European Community (EC) Number:263-421-0
DSSTox Substance ID:DTXSID10211185
Nikkaji Number:J306.990G
Wikidata:Q83086037
ChEMBL ID:CHEMBL2035660

Synonyms:62124-77-0;ETHYL 3-(2-PYRAZINYL)-3-OXOPROPANOATE;ETHYL 3-OXO-3-PYRAZIN-2-YL-PROPIONATE;ETHYL 3-OXO-3-(PYRAZIN-2-YL)PROPANOATE;ethyl 3-oxo-3-pyrazin-2-ylpropanoate;Ethyl beta-oxopyrazinepropionate;EINECS 263-421-0;MFCD04114374;Ethyl3-(2-Pyrazinyl)-3-oxopropanoate;SCHEMBL509677;CHEMBL2035660;DTXSID10211185;OPBDMDPBJKVMNL-UHFFFAOYSA-N;AMY20475;AKOS010951955;AB18180;CS-11106;Ethyl 3-Oxo-3-(pyrazin-2-yl)propionate;SY005599;E1271;FT-0693322;beta-Oxo-2-pyrazinepropionic acid ethyl ester;3-Oxo-3-pyrazin-2-yl-propionic acid, ethyl ester;A833594;3-Oxo-3-(pyrazin-2-yl)propionic Acid Ethyl Ester;ethyl 3-oxo-3-pyrazin-2-yl-propanoate;Ethyl 3-(2-Pyrazinyl)-3-oxopropanoate

Suppliers and Price of Ethyl 3-(2-pyrazinyl)-3-oxopropanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Ethyl 3-Oxo-3-(pyrazin-2-yl)propionate
100mg
$ 45.00

TCI Chemical
Ethyl 3-Oxo-3-(pyrazin-2-yl)propionate >98.0%(GC)(T)
1g
$ 131.00

Sigma-Aldrich
Ethyl 3-oxo-3-(pyrazin-2-yl)propanoate
1 g
$ 140.00

J&W Pharmlab
Ethyl 3-Oxo-3-(pyrazin-2-yl)propionate 96%
25g
$ 840.00

J&W Pharmlab
Ethyl 3-Oxo-3-(pyrazin-2-yl)propionate 96%
5g
$ 225.00

J&W Pharmlab
Ethyl 3-Oxo-3-(pyrazin-2-yl)propionate 96%
1g
$ 60.00

Heterocyclics
Ethyl 3-oxo-3-(pyrazin-2-yl)propanoate 97%
1g
$ 55.00

Heterocyclics
Ethyl 3-oxo-3-(pyrazin-2-yl)propanoate 97%
5g
$ 169.00

Heterocyclics
Ethyl 3-oxo-3-(pyrazin-2-yl)propanoate 97%
25g
$ 676.00

Crysdot
Ethyl 3-oxo-3-(pyrazin-2-yl)propanoate 97%
25g
$ 1064.00

Total 19 raw suppliers

Chemical Property of Ethyl 3-(2-pyrazinyl)-3-oxopropanoate

Chemical Property:

Melting Point:61.0 to 65.0 °C
Boiling Point:120°C/2mmHg(lit.)
Flash Point:129.9oC
PSA：69.15000
Density:1.21g/cm3
LogP:0.61250
XLogP3:0.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:194.06914219
Heavy Atom Count:14
Complexity:218

Purity/Quality:

97% ^*data from raw suppliers

Ethyl 3-Oxo-3-(pyrazin-2-yl)propionate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)CC(=O)C1=NC=CN=C1

Technology Process of Ethyl 3-(2-pyrazinyl)-3-oxopropanoate

There total 7 articles about Ethyl 3-(2-pyrazinyl)-3-oxopropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 141-78-6
ethyl acetate

: 6924-68-1
ethyl 2-pyrazinecarboxylate

: 62124-77-0
3-oxo-3-pyrazin-2-yl-propionic acid ethyl ester

: 141-97-9
ethyl acetoacetate

Guidance literature:: With lithium hexamethyldisilazane; In tetrahydrofuran; at -40 ℃; for 0.333333h; Inert atmosphere;
DOI:10.1016/j.bmcl.2012.04.008

Reference yield: 82.0%

: 98-97-5
2-pyrazylcarboxylic acid

: 1071-46-1
hydrogen ethyl malonate

: 62124-77-0
3-oxo-3-pyrazin-2-yl-propionic acid ethyl ester

Guidance literature:: 2-pyrazylcarboxylic acid; With 1,1'-carbonyldiimidazole; In tetrahydrofuran; for 2h; Reflux;

hydrogen ethyl malonate; With methylmagnesium bromide; In tetrahydrofuran; diethyl ether; water; at 0 ℃; Reflux;
DOI:10.1021/jm500462x