3,3-dimethyl-2-methylidenebicyclo[2.2.1]heptan-1-ol

Base Information

• Chemical Name: 3,3-dimethyl-2-methylidenebicyclo[2.2.1]heptan-1-ol
• CAS No.: 22780-14-9
• Molecular Formula: C10H16 O
• Molecular Weight: 152.236
• Mol file: 22780-14-9.mol

Synonyms:1-Norbornanol,3,3-dimethyl-2-methylene- (6CI,8CI); 1-Hydroxycamphene; NSC 368165

Chemical Property of 3,3-dimethyl-2-methylidenebicyclo[2.2.1]heptan-1-ol

Chemical Property:

• Vapor Pressure: 0.0858mmHg at 25°C
• Boiling Point: 199.4°Cat760mmHg
• Flash Point: 79°C
• Density: 1.01g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,3-dimethyl-2-methylidenebicyclo[2.2.1]heptan-1-ol

There total 12 articles about 3,3-dimethyl-2-methylidenebicyclo[2.2.1]heptan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

3,3-Dimethyl-2-methylene-bicyclo[2.2.1]hept-1-yl trifluoromethane-sulfonate (61136-72-9) → 1-Hydroxycamphen (22780-14-9)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; for 48h; Ambient temperature;

Reference yield: 95.0%

(1R)-3,3-dimethyl-2-methylenenorborn-1-yl triflate (140147-15-5) → (1R)-3,3-dimethyl-2-methylenenorbornan-1-ol (22780-14-9)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether;

DOI:10.1016/S0957-4166(00)00279-2

Reference yield: 67.0%

ethanol (64-17-5) + 1-camphenyl triflate (61136-72-9,63028-06-8,140147-15-5) → (1S,4S)-3,3-Dimethyl-2-methylene-bicyclo[2.2.1]heptan-1-ol (22780-14-9) + (1S,4S)-1-Ethoxy-3,3-dimethyl-2-methylene-bicyclo[2.2.1]heptane (68592-35-8)

Guidance literature:

In water; at 60 ℃; for 24h;

DOI:10.1016/S0040-4039(00)99502-9

upstream raw materials:

3,3-Dimethyl-2-methylene-bicyclo[2.2.1]hept-1-yl trifluoromethane-sulfonate

(1R)-3,3-dimethyl-2-methyliden-1-norbornylamine

water

(1R)-3,3-dimethyl-2-methylenenorborn-1-yl triflate

Downstream raw materials:

formaldehyd

(1R,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one

(1R,4R)-1-hydroxymethyl-7,7-dimethyl-bicyclo[2.2.1]heptan-2-one