2,2,2-Trifluoro-1-(p-tolyl)ethanol

Base Information

Chemical Name:2,2,2-Trifluoro-1-(p-tolyl)ethanol
CAS No.:446-65-1
Molecular Formula:C9H9F3O
Molecular Weight:190.165
Hs Code.:2906290090
NSC Number:405748
DSSTox Substance ID:DTXSID50324107
Nikkaji Number:J978.888C
Mol file:446-65-1.mol

Synonyms:2,2,2-Trifluoro-1-(p-tolyl)ethanol;446-65-1;2,2,2-trifluoro-1-p-tolylethanol;2,2,2-trifluoro-1-(4-methylphenyl)ethanol;MFCD00233111;NSC405748;alpha-(Trifluoromethyl)-4-methylbenzyl Alcohol;SCHEMBL307896;DTXSID50324107;AKOS001287912;AKOS016845550;CS-W021468;DS-6944;NSC-405748;p-methyl-a-trifluoromethylbenzyl alcohol;SY114644;alpha-Trifluoromethyl-4-methylbenzyl alcohol;4-(2,2,2-trifluoro-1-hydroxyethyl)toluene;1-(4-methylphenyl)-2,2,2-trifluoro-ethanol;EN300-24370;2,2,2-trifluoro-1-(4-methylphenyl)ethan-1-ol;A872483;J-506747;Z188898086

Suppliers and Price of 2,2,2-Trifluoro-1-(p-tolyl)ethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 15 raw suppliers

Chemical Property of 2,2,2-Trifluoro-1-(p-tolyl)ethanol

Chemical Property:

Vapor Pressure:0.036mmHg at 25°C
Boiling Point:230.8°Cat760mmHg
Flash Point:102.5°C
PSA：20.23000
Density:1.241g/cm³
LogP:2.59070
Storage Temp.:Keep in dark place,Sealed in dry,Room Temperature
XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:190.06054939
Heavy Atom Count:13
Complexity:159

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C(C(F)(F)F)O

Technology Process of 2,2,2-Trifluoro-1-(p-tolyl)ethanol

There total 16 articles about 2,2,2-Trifluoro-1-(p-tolyl)ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 446-65-1
2,2,2-trifluoro-1-(4-methylphenyl)ethanol

Guidance literature:

Reference yield: 98.0%

: 104-87-0
4-methyl-benzaldehyde

: 81290-20-2
(trifluoromethyl)trimethylsilane

: 446-65-1
2,2,2-trifluoro-1-(4-methylphenyl)ethanol

Guidance literature:: 4-methyl-benzaldehyde; (trifluoromethyl)trimethylsilane; With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 4h;

With water; In N,N-dimethyl-formamide; for 4h; Acidic conditions;
DOI:10.1016/j.tetlet.2013.06.045

Reference yield: 96.0%

: 2923-18-4
sodium 2,2,2-trifluoroacetate

: 104-87-0
4-methyl-benzaldehyde

: 446-65-1
2,2,2-trifluoro-1-(4-methylphenyl)ethanol

Guidance literature:: sodium 2,2,2-trifluoroacetate; 4-methyl-benzaldehyde; With copper(l) iodide; In N,N-dimethyl-formamide; at 170 ℃; for 2h;

With hydrogenchloride; In N,N-dimethyl-formamide; at 170 ℃; for 4h;
DOI:10.1016/j.jfluchem.2005.04.012