naphthalen-2-yl chloroacetate

Base Information

• Chemical Name: naphthalen-2-yl chloroacetate
• CAS No.: 26177-06-0
• Molecular Formula: C12H9 Cl O2
• Molecular Weight: 220.655
• Mol file: 26177-06-0.mol

Synonyms:Aceticacid, chloro-, 2-naphthalenyl ester (9CI); Acetic acid, chloro-, 2-naphthylester (6CI,7CI,8CI); 2-Naphthol, chloroacetate (8CI); 2-Naphthyl chloroacetate;NSC 8383; b-Naphthyl chloroacetate

Chemical Property of naphthalen-2-yl chloroacetate

Chemical Property:

• Vapor Pressure: 6.09E-05mmHg at 25°C
• Boiling Point: 345.6°Cat760mmHg
• Flash Point: 179.7°C
• Density: 1.278g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of naphthalen-2-yl chloroacetate

There total 1 articles about naphthalen-2-yl chloroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

trichloroacetic acid naphthalen-2-yl ester (1871-41-6) → 2-naphthyl α-chloroacetate (26177-06-0) + β-naphthol (135-19-3)

Guidance literature:

With [2,2]bipyridinyl; copper(l) chloride; In 1,2-dichloro-ethane; for 1h; Solvent; Schlenk technique; Inert atmosphere; Reflux; Cooling with ice;

DOI:10.1016/j.molstruc.2019.02.018

Reference yield: 91.0%

2-naphthyl α-chloroacetate (26177-06-0) → β-naphthol (135-19-3)

Guidance literature:

With disodium telluride; In N,N-dimethyl-formamide; for 1h; Ambient temperature;

Reference yield:

2-naphthyl α-chloroacetate (26177-06-0) + ethyl iodide (75-03-6) → 2-ethoxynaphthalene (93-18-5) + diethyltellurium diiodide

Guidance literature:

With disodium telluride; Yield given. Multistep reaction. Yields of byproduct given; 1.) DMF, r.t., 10 min; 2.) r.t., 30 min; 3.) 50 deg C, 2 h;

upstream raw materials:

trichloroacetic acid naphthalen-2-yl ester

Downstream raw materials:

β-naphthol

2-ethoxynaphthalene

naphtho[2,1-b]furan