6H-CYCLOHEPTA(b)QUINOLINE, 7,8,9,10-TETRAHYDRO-11-AMINO-

Base Information

Chemical Name:6H-CYCLOHEPTA(b)QUINOLINE, 7,8,9,10-TETRAHYDRO-11-AMINO-
CAS No.:5778-86-9
Molecular Formula:C14H16N2
Molecular Weight:212.2902
Hs Code.:2933990090
DSSTox Substance ID:DTXSID00206469
Nikkaji Number:J63.322D
Wikidata:Q83080296
Pharos Ligand ID:6QUWSD2T4V5F
ChEMBL ID:CHEMBL330883
Mol file:5778-86-9.mol

Synonyms:5778-86-9;7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-amine;MAS 111;6H-CYCLOHEPTA(b)QUINOLINE, 7,8,9,10-TETRAHYDRO-11-AMINO-;11-Amino-7,8,9,10-Tetrahydro-6h-Cyclohepta[B]Quinoline;BRN 0474991;CHEMBL330883;7,8,9,10-Tetrahydro-11-amino-6H-cyclohepta(b)quinoline;5-22-10-00499 (Beilstein Handbook Reference);CBMicro_016170;Oprea1_071042;Oprea1_392057;SCHEMBL5042118;7,8,9,10-Tetrahydro-6H-cyclohepta[b]quinolin-11-ylamine;DTXSID00206469;MAS-111;4-amino-2,3-pentamethylenequinoline;BDBM50060483;AKOS000663989;LS-56080;A18925;E79701

Suppliers and Price of 6H-CYCLOHEPTA(b)QUINOLINE, 7,8,9,10-TETRAHYDRO-11-AMINO-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
11-AMINO-7,8,9,10-TETRAHYDRO-6H-CYCLOHEPTA[B]QUINOLINE 95.00%
5MG
$ 496.68

Total 7 raw suppliers

Chemical Property of 6H-CYCLOHEPTA(b)QUINOLINE, 7,8,9,10-TETRAHYDRO-11-AMINO-

Chemical Property:

Vapor Pressure:2.84E-07mmHg at 25°C
Boiling Point:420.3°Cat760mmHg
Flash Point:237.5°C
PSA：39.64000
Density:1.156g/cm³
LogP:3.01600
XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:212.131348519
Heavy Atom Count:16
Complexity:241

Purity/Quality:

97% ^*data from raw suppliers

11-AMINO-7,8,9,10-TETRAHYDRO-6H-CYCLOHEPTA[B]QUINOLINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CCC2=C(C3=CC=CC=C3N=C2CC1)N

Technology Process of 6H-CYCLOHEPTA(b)QUINOLINE, 7,8,9,10-TETRAHYDRO-11-AMINO-

There total 2 articles about 6H-CYCLOHEPTA(b)QUINOLINE, 7,8,9,10-TETRAHYDRO-11-AMINO- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 1885-29-6
anthranilic acid nitrile

: 502-42-1
cycloheptanone

: 5778-86-9
7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-ylamine

Guidance literature:: With sulfuric acid-modified polyethylene glycol 6000; at 130 ℃; for 0.15h; Microwave irradiation; Neat (no solvent);
DOI:10.1039/c0gc00953a

Reference yield:

: 5778-86-9
7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-ylamine

Guidance literature:

Reference yield:

: 5778-86-9
7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-ylamine

: (E)-2-(3-((4-fluorophenyl)imino)-2-oxoindolin-1-yl)-N-(7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-yl)acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: boron trifluoride / dichloromethane / 20 °C / Cooling with ice

2: potassium carbonate / N,N-dimethyl-formamide / 20 °C / Inert atmosphere

With boron trifluoride; potassium carbonate; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.2174/1386207323666201211092138