Benzamide, 4-methoxy-N-(3-(4-morpholinyl)propyl)-

Base Information

• Chemical Name: Benzamide, 4-methoxy-N-(3-(4-morpholinyl)propyl)-
• CAS No.: 5460-28-6
• Molecular Formula: C15H22N2O3
• Molecular Weight: 278.3468
• NSC Number: 25104
• DSSTox Substance ID: DTXSID80203032
• Wikidata: Q83076396
• ChEMBL ID: CHEMBL1877431
• Mol file: 5460-28-6.mol

Synonyms:5460-28-6;Benzamide, 4-methoxy-N-(3-(4-morpholinyl)propyl)-;4-Methoxy-N-(3-(4-morpholinyl)propyl)benzamide;4-methoxy-N-[3-(4-morpholinyl)propyl]benzamide;benzamide, 4-methoxy-n-[3-(4-morpholinyl)propyl]-;BRN 4296080;NSC25104;Cambridge id 5161531;Cerep_000157;4-Methoxy-N-(3-morpholin-4-yl-propyl)-benzamide;4-methoxy-N-[3-(morpholin-4-yl)propyl]benzamide;CBDivE_003683;MLS001209578;CHEMBL1877431;SCHEMBL10379079;HMS526H19;DTXSID80203032;HMS2828M11;NSC 25104;NSC-25104;STK180714;AKOS003245231;NCGC00245360-01;SMR000518416;AB00074726-01;Z31815596

Chemical Property of Benzamide, 4-methoxy-N-(3-(4-morpholinyl)propyl)-

Chemical Property:

• Vapor Pressure: 5.05E-09mmHg at 25°C
• Boiling Point: 470.5°Cat760mmHg
• Flash Point: 238.3°C
• Density: 1.107g/cm³
• XLogP3: 1.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 6
• Exact Mass: 278.16304257
• Heavy Atom Count: 20
• Complexity: 285

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)C(=O)NCCCN2CCOCC2

Technology Process of Benzamide, 4-methoxy-N-(3-(4-morpholinyl)propyl)-

There total 2 articles about Benzamide, 4-methoxy-N-(3-(4-morpholinyl)propyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

4-(3-Aminopropyl)morpholine (123-00-2) + 4-methoxy-benzoyl chloride (100-07-2) → 4-methoxy-N-(3-morpholinopropyl)benzamide (5460-28-6)

Guidance literature:

In chloroform; at 40 - 50 ℃; for 0.333333h;

DOI:10.1007/BF00764609

Reference yield: 66.0%

4-(3-Aminopropyl)morpholine (123-00-2) + 4-Methoxybenzenethiol (696-63-9) + carbon monoxide (201230-82-2) → 4-methoxy-N-(3-morpholinopropyl)benzamide (5460-28-6)

Guidance literature:

With dicobalt octacarbonyl; In toluene; at 220 ℃; for 1h; under 11251.1 Torr; Reagent/catalyst; Inert atmosphere;

DOI:10.1039/d1ra04736a

upstream raw materials:

4-(3-Aminopropyl)morpholine

4-methoxy-benzoyl chloride

4-Methoxybenzenethiol

carbon monoxide