a-(AMinoMethyl)-a-phenyl-benzeneMethanol

Base Information

• Chemical Name: a-(AMinoMethyl)-a-phenyl-benzeneMethanol
• CAS No.: 4382-96-1
• Molecular Formula: C14H15NO
• Molecular Weight: 213.279
• Hs Code.: 2922199090
• Mol file: 4382-96-1.mol

Synonyms:2,2-diphenyl-2-hydroxyethylamine;Aminomethyl-diphenyl-carbinol;a-(Aminomethyl)-a-phenyl-benzenemethanol;2-amino-1,1-diphenyl-ethanol;2-Amino-1,1-diphenyl-aethanol;

Chemical Property of a-(AMinoMethyl)-a-phenyl-benzeneMethanol

Chemical Property:

• PSA: 46.25000
• LogP: 2.58150

Purity/Quality:

ALPHA-(AMINOMETHYL)-ALPHA-PHENYL-BENZENEMETHANOL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of a-(AMinoMethyl)-a-phenyl-benzeneMethanol

There total 25 articles about a-(AMinoMethyl)-a-phenyl-benzeneMethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

Cbz-2-amino-1,1-diphenylethanol → 2-amino-1,1-diphenylethanol (4382-96-1)

Guidance literature:

With 5%-palladium/activated carbon; hydrogen; In methanol; at 50 ℃;

DOI:10.1002/aoc.3347

Reference yield: 81.0%

2-aminoacetophenone hydrochloride (5468-37-1) + phenylmagnesium bromide (100-58-3) → 2-amino-1,1-diphenylethanol (4382-96-1)

Guidance literature:

In tetrahydrofuran; at 45 ℃; for 3h;

DOI:10.1039/c3ob40463c

Reference yield: 70.0%

2-azido-1,1-diphenylethan-1-ol (155694-19-2) → 2-amino-1,1-diphenylethanol (4382-96-1)

Guidance literature:

With sodium tetrahydroborate; In isopropyl alcohol; Heating;

DOI:10.1016/S0040-4039(00)76747-5

upstream raw materials:

acetophenone oxime

hydroxy-diphenyl-acetaldehyde-oxime

glycine ethyl ester hydrochloride

GlyOEt*HCl

Downstream raw materials:

phenyl benzyl ketone

Diphenylacetaldehyde

2,2-diphenyl-vinylamine

(2,2-diphenyl-ethylidene)-(2,2-diphenyl-vinyl)-amine