Phosphinic chloride, bis(chloromethyl)-

Base Information

• Chemical Name: Phosphinic chloride, bis(chloromethyl)-
• CAS No.: 13482-64-9
• Molecular Formula: C2H4 Cl3 O P
• Molecular Weight: 181.386
• DSSTox Substance ID: DTXSID50158964
• Nikkaji Number: J696.640C
• Mol file: 13482-64-9.mol

Synonyms:Phosphinic chloride, bis(chloromethyl)-;13482-64-9;SCHEMBL7719749;DTXSID50158964;XBTTVJBCKILSKP-UHFFFAOYSA-N;bis(chloromethyl)phosphinic chloride;bis(chloromethyl)phosphinoyl chloride

Chemical Property of Phosphinic chloride, bis(chloromethyl)-

Chemical Property:

• Vapor Pressure: 0.000574mmHg at 25°C
• Boiling Point: 321°C at 760 mmHg
• Flash Point: 148°C
• Density: 1.513g/cm³
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 179.906535
• Heavy Atom Count: 7
• Complexity: 84.9

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(P(=O)(CCl)Cl)Cl

Technology Process of Phosphinic chloride, bis(chloromethyl)-

There total 2 articles about Phosphinic chloride, bis(chloromethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

bis(hydroxymethyl)phosphinic acid (2074-67-1) → bis(chloromethyl)phosphinic chloride (13482-64-9) + chloromethylphosphonic dichloride (1983-26-2)

Guidance literature:

With phosphorus pentachloride; trichlorophosphate;

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) → bis(chloromethyl)phosphinic chloride (13482-64-9) + chloromethylphosphonic dichloride (1983-26-2)

Guidance literature:

formaldehyd; With hydrogenchloride; sodium hypophosphite; isobutyric Acid; at 60 - 75 ℃; for 30h;

With phosphorus pentachloride; trichlorophosphate; at 40 - 70 ℃; for 4h;

Reference yield: 90.0%

bis(chloromethyl)phosphinic chloride (13482-64-9) + aniline (62-53-3) → Bis-chlormethyl-phosphinsaeure-anilid (17166-98-2)

Guidance literature:

In diethyl ether; for 3h; Ambient temperature;

upstream raw materials:

bis(hydroxymethyl)phosphinic acid

formaldehyd

Downstream raw materials:

Bis-chlormethyl-phosphinsaeure-methylester

ethyl bis(chloromethyl)phosphinate

4-nitrophenyl bis(chloromethyl)phosphinate

Bis-chloromethyl-phosphinic acid 2,4-dichloro-phenyl ester

Refernces

• 1、 Nazarov, Yu. V.,Muslinkin, A. A.,Kutuev, A. A.. "Optimization of Synthesis of Bis(chloromethyl)phosphinic Chloride". . p. 141 - 143. Retrieved 2007/10/03.