N-tert-butylpyridine-2-carboxamide

Base Information

Chemical Name:N-tert-butylpyridine-2-carboxamide
CAS No.:71653-50-4
Molecular Formula:C₁₀H₁₄N₂O
Molecular Weight:178.234
Hs Code.:
DSSTox Substance ID:DTXSID301339077
Nikkaji Number:J702.209C

Synonyms:N-tert-butylpyridine-2-carboxamide;picolinic acid t-butylamide;71653-50-4;SCHEMBL1834472;IDSCGIREUASONG-UHFFFAOYSA-N;DTXSID301339077;AKOS008949317;N-(2-Methyl-2-propanyl)-2-pyridinecarboxamide

Suppliers and Price of N-tert-butylpyridine-2-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-tert-butylpyridine-2-carboxamide

Chemical Property:

XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:178.110613074
Heavy Atom Count:13
Complexity:184

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)NC(=O)C1=CC=CC=N1

Technology Process of N-tert-butylpyridine-2-carboxamide

There total 1 articles about N-tert-butylpyridine-2-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 110-86-1
pyridine

: 119072-55-8,7188-38-7
tert-butylisonitrile

: 109-09-1
2-chloropyridine

: 71653-50-4
pyridine-2-carboxylic acid N-tert-butylamide

: N-tert-butyl-2-oxo-2-pyridin-2-yl-acetamide

Guidance literature:: pyridine; With fluorine; In dichloromethane; at -78 - -50 ℃;

tert-butylisonitrile; In dichloromethane; at -50 - 0 ℃; for 4h;
DOI:10.1016/j.tetlet.2005.02.010

Reference yield: 82.0%

: 71653-50-4
pyridine-2-carboxylic acid N-tert-butylamide

: 86-81-7
3,4,5-trimethoxy-benzaldehyde

: 1021463-83-1
N-(tert-butyl)-3-[(hydroxy)(3,4,5-trimethoxyphenyl)methyl]pyridine-2-carboxamide

Guidance literature:: With lithium tributyl magnesiate; In tetrahydrofuran; at 20 ℃; for 2h;
DOI:10.1016/j.tet.2008.01.064

Reference yield: 74.0%

: 637-59-2
1-Bromo-3-phenylpropane

: 71653-50-4
pyridine-2-carboxylic acid N-tert-butylamide

: N-(tert-butyl)-3-(3-phenylpropyl)picolinamide

Guidance literature:: With N,N,N,N,-tetramethylethylenediamine; neopentylmagnesium bromide; manganese(ll) chloride; In tetrahydrofuran; at 60 ℃; for 14h; chemoselective reaction; Schlenk technique; Inert atmosphere;
DOI:10.1021/acs.orglett.8b03924