alpha-((1-((2-ethyl-5,7-dimethylimidazo(4,5-b)pyridin-3-yl)methyl)-3,5-dipropylphenyl-4-yl)oxy)phenylacetic acid

Base Information

Chemical Name:alpha-((1-((2-ethyl-5,7-dimethylimidazo(4,5-b)pyridin-3-yl)methyl)-3,5-dipropylphenyl-4-yl)oxy)phenylacetic acid
CAS No.:153275-22-0
Molecular Formula:C31H37 N3 O3
Molecular Weight:499.64
Hs Code.:
Mol file:153275-22-0.mol

Synonyms:Benzeneaceticacid, a-[4-[(2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl)methyl]-2,6-dipropylphenoxy]-,(?à)-; 3H-Imidazo[4,5-b]pyridine,benzeneacetic acid deriv.; L 159882

Suppliers and Price of alpha-((1-((2-ethyl-5,7-dimethylimidazo(4,5-b)pyridin-3-yl)methyl)-3,5-dipropylphenyl-4-yl)oxy)phenylacetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of alpha-((1-((2-ethyl-5,7-dimethylimidazo(4,5-b)pyridin-3-yl)methyl)-3,5-dipropylphenyl-4-yl)oxy)phenylacetic acid

Chemical Property:

Vapor Pressure:1.52E-18mmHg at 25°C
Boiling Point:664.1°Cat760mmHg
Flash Point:355.5°C
PSA：77.24000
Density:1.15g/cm³
LogP:6.76850

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of alpha-((1-((2-ethyl-5,7-dimethylimidazo(4,5-b)pyridin-3-yl)methyl)-3,5-dipropylphenyl-4-yl)oxy)phenylacetic acid

There total 23 articles about alpha-((1-((2-ethyl-5,7-dimethylimidazo(4,5-b)pyridin-3-yl)methyl)-3,5-dipropylphenyl-4-yl)oxy)phenylacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 137421-58-0
3-[4-((1-carbomethoxy-1-phenyl)methoxy)-3,5-dipropylphenylmethyl]-5,7-dimethyl-2-ethyl-3H-imidazo-[4,5-b]pyridine

: 153275-22-0
L 159882

Guidance literature:

Reference yield:

: 53596-60-4
methyl 3-allyl-4-hydroxybenzoate

: 153275-22-0
L 159882

Guidance literature:: Multi-step reaction with 9 steps

1: 87 percent / K₂CO₃ / acetone / Heating

2: 94 percent / 2,6-di-tert-butyl-4-methylphenol (BHT) / various solvent(s) / Heating

3: 97 percent / Et₃N, DMAP / CH₂Cl₂

4: 90 percent / H₂ / 5percent Rh/C / ethanol

5: 92 percent / LiAlH₄ / tetrahydrofuran / 0 - 20 °C

6: 82 percent / Ph₃P, DEAD / tetrahydrofuran / 0 °C

7: 93 percent / n-Bu₄NF / tetrahydrofuran

8: K₂CO₃ / acetone / Heating

9: 1 N aq. NaOH / methanol

With dmap; sodium hydroxide; lithium aluminium tetrahydride; 2,6-di-tert-butyl-4-methyl-phenol; tetrabutyl ammonium fluoride; hydrogen; potassium carbonate; triethylamine; triphenylphosphine; diethylazodicarboxylate; Rh on carbon; In tetrahydrofuran; methanol; ethanol; dichloromethane; acetone;
DOI:10.1021/jm00075a033

Reference yield:

: 99-76-3,156291-94-0
methyl 4-hydroxylbenzoate

: 153275-22-0
L 159882

Guidance literature:: Multi-step reaction with 11 steps

1: 89 percent / K₂CO₃ / acetone / Heating

2: 90 percent / 2,6-di-tert-butyl-4-methylphenol (BHT) / various solvent(s) / Heating

3: 87 percent / K₂CO₃ / acetone / Heating

4: 94 percent / 2,6-di-tert-butyl-4-methylphenol (BHT) / various solvent(s) / Heating

5: 97 percent / Et₃N, DMAP / CH₂Cl₂

6: 90 percent / H₂ / 5percent Rh/C / ethanol

7: 92 percent / LiAlH₄ / tetrahydrofuran / 0 - 20 °C

8: 82 percent / Ph₃P, DEAD / tetrahydrofuran / 0 °C

9: 93 percent / n-Bu₄NF / tetrahydrofuran

10: K₂CO₃ / acetone / Heating

11: 1 N aq. NaOH / methanol

With dmap; sodium hydroxide; lithium aluminium tetrahydride; 2,6-di-tert-butyl-4-methyl-phenol; tetrabutyl ammonium fluoride; hydrogen; potassium carbonate; triethylamine; triphenylphosphine; diethylazodicarboxylate; Rh on carbon; In tetrahydrofuran; methanol; ethanol; dichloromethane; acetone;
DOI:10.1021/jm00075a033