spiro[1,3-dioxolane-2,3'-indol]-2'(1'H)-one

Base Information

Chemical Name:spiro[1,3-dioxolane-2,3'-indol]-2'(1'H)-one
CAS No.:6714-68-7
Molecular Formula:C10H9 N O3
Molecular Weight:191.186
Hs Code.:2933990090
NSC Number:133703
DSSTox Substance ID:DTXSID10299923
Nikkaji Number:J1.947.154C
Wikidata:Q82042637
ChEMBL ID:CHEMBL6816
Mol file:6714-68-7.mol

Synonyms:6714-68-7;spiro[1,3-dioxolane-2,3'-indol]-2'(1'H)-one;Spiro-(1,3-dioxolane-2,3'indolin)-2'-one;Spiro[[1,3]dioxolane-2,3'-indolin]-2'-one;spiro[1,3-dioxolane-2,3'-1H-indole]-2'-one;NSC 133703;Spiro[1,3-dioxolane-2,3'-[3H]indol]-2'(1'H)-one;Spiro[1,3-dioxolane-2,3//'-indol]-2//'(1//'H)-one;Spiro[1,3-dioxolane-2,3'-[3H]indol]-2'(1'H]-one;NSC133703;Maybridge1_007498;ChemDiv1_000004;CHEMBL6816;Oprea1_094196;Oprea1_647993;MLS000056788;SCHEMBL9053384;HMS562M18;HMS587A04;DTXSID10299923;HMS2494D16;CCG-55937;MFCD00173689;STK391101;AKOS000491085;NSC-133703;SDCCGMLS-0023117.P002;Indol-2(3H)-one, 3,3-ethylenedioxy-;LS-05313;SMR000065849;CS-0348819;FT-0636244;3,3-(Ethylenebisoxy)-1H-indole-2(3H)-one;Spiro[1,3-dioxolane-2,3'-indolin]-2'-one;spiro[indoline-3,2'-[1,3]dioxolan]-2-one;AE-641/30402015;SPIRO-(1,3-DIOXOLANE-2,3INDOLIN)-2-ONE;SR-01000390546;SR-01000390546-1;SR-01000390546-3;Spiro[1,3-dioxolane-2,3/'-indol]-2/'(1/'H)-one;Z56788822;1',2'-dihydrospiro[1,3-dioxolane-2,3'-indol]-2'-one;F1443-1058;1,3-dihydrospiro[(2H)-indole-3,2'-[1,3]-dioxolane]-2-one

Suppliers and Price of spiro[1,3-dioxolane-2,3'-indol]-2'(1'H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
Spiro[1,3-dioxolane-2,3'-indol]-2'(1'H)-one
500mg
$ 72.00

Matrix Scientific
Spiro[1,3-dioxolane-2,3'-indol]-2'(1'H)-one
1g
$ 322.00

Crysdot
Spiro[[1,3]dioxolane-2,3'-indolin]-2'-one 95+%
5g
$ 306.00

Crysdot
Spiro[[1,3]dioxolane-2,3'-indolin]-2'-one 95+%
10g
$ 424.00

Chemenu
Spiro[[1,3]dioxolane-2,3''-indolin]-2''-one 95%
10g
$ 400.00

Chemenu
Spiro[[1,3]dioxolane-2,3''-indolin]-2''-one 95%
5g
$ 289.00

Aronis compounds
spiro[1,3-dioxolane-2,3'-indol]-2'(1'H)-one
20mg
$ 30.00

Aronis compounds
spiro[1,3-dioxolane-2,3'-indol]-2'(1'H)-one
100mg
$ 80.00

American Custom Chemicals Corporation
SPIRO-(1,3-DIOXOLANE-2,3'INDOLIN)-2'-ONE 95.00%
5G
$ 970.20

American Custom Chemicals Corporation
SPIRO-(1,3-DIOXOLANE-2,3'INDOLIN)-2'-ONE 95.00%
1G
$ 646.80

Total 16 raw suppliers

Chemical Property of spiro[1,3-dioxolane-2,3'-indol]-2'(1'H)-one

Chemical Property:

Melting Point:125oC
Boiling Point:408.3oC at 760 mmHg
Flash Point:200.8oC
PSA：47.56000
Density:1.4g/cm3
LogP:0.97630
XLogP3:0.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:191.058243149
Heavy Atom Count:14
Complexity:260

Purity/Quality:

98% ^*data from raw suppliers

Spiro[1,3-dioxolane-2,3'-indol]-2'(1'H)-one ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COC2(O1)C3=CC=CC=C3NC2=O

Technology Process of spiro[1,3-dioxolane-2,3'-indol]-2'(1'H)-one

There total 6 articles about spiro[1,3-dioxolane-2,3'-indol]-2'(1'H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 91-56-5,1186480-61-4,84788-92-1
indole-2,3-dione

: 107-21-1
ethylene glycol

: 6714-68-7
spiro[1,3-dioxolane-2,3'-indolin]-2'-one

Guidance literature:: With toluene-4-sulfonic acid; In benzene; for 5h; Heating;
DOI:10.1021/jm00085a001

Reference yield: 95.0%

: 91-56-5,1186480-61-4,84788-92-1
indole-2,3-dione

: 540-51-2
2-bromoethanol

: 6714-68-7
spiro[1,3-dioxolane-2,3'-indolin]-2'-one

Guidance literature:: indole-2,3-dione; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 0.166667h;

2-bromoethanol; In N,N-dimethyl-formamide; at 20 - 70 ℃; for 1.25h;
DOI:10.1021/om4009229