2-phenyl-4H-pyrido[1,2-a]pyrimidin-4-one

Base Information

Chemical Name:2-phenyl-4H-pyrido[1,2-a]pyrimidin-4-one
CAS No.:16054-93-6
Molecular Formula:C14H10N2O
Molecular Weight:222.246
Hs Code.:2933990090
NSC Number:156830
DSSTox Substance ID:DTXSID60303120
Nikkaji Number:J2.276.356C
Wikidata:Q72498566
ChEMBL ID:CHEMBL241975
Mol file:16054-93-6.mol

Synonyms:2-phenyl-4H-pyrido[1,2-a]pyrimidin-4-one;16054-93-6;2-phenylpyrido[1,2-a]pyrimidin-4-one;CHEMBL241975;NSC156830;SCHEMBL1659994;DTXSID60303120;BDBM50221753;MFCD06637703;STL582069;AKOS015831073;NSC-156830;LS-05489;CS-0324254

Suppliers and Price of 2-phenyl-4H-pyrido[1,2-a]pyrimidin-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-Phenyl-4H-pyrido[1,2-a]pyrimidin-4-one 95+%
5g
$ 792.00

AK Scientific
2-Phenyl-4H-pyrido[1,2-a]pyrimidin-4-one
500mg
$ 369.00

Total 9 raw suppliers

Chemical Property of 2-phenyl-4H-pyrido[1,2-a]pyrimidin-4-one

Chemical Property:

Vapor Pressure:0.00482mmHg at 25°C
Refractive Index:1.64
Boiling Point:396.9 °C at 760mmHg
Flash Point:193.8 °C
PSA：34.37000
Density:1.19 g/cm³
LogP:2.36150
XLogP3:1.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:222.079312947
Heavy Atom Count:17
Complexity:451

Purity/Quality:

98%min ^*data from raw suppliers

2-Phenyl-4H-pyrido[1,2-a]pyrimidin-4-one 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=CC(=O)N3C=CC=CC3=N2

Technology Process of 2-phenyl-4H-pyrido[1,2-a]pyrimidin-4-one

There total 19 articles about 2-phenyl-4H-pyrido[1,2-a]pyrimidin-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 504-29-0
2-aminopyridine

: 94-02-0
ethyl 3-oxo-3-phenylpropionate

: 16054-93-6
2-phenyl-4H-pyrido[1,2-a]pyrimidin-4-one

Guidance literature:: With Al₃PW₁₂O₄₀; In ethanol; at 80 ℃; for 0.266667h; Green chemistry;
DOI:10.1039/c5ra22180c

Reference yield: 91.0%

: 5418-94-0
2-chloro-4H-pyrido[1,2-a]pyrimidin-4-one

: 98-80-6
phenylboronic acid

: 16054-93-6
2-phenyl-4H-pyrido[1,2-a]pyrimidin-4-one

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium hydrogencarbonate; In 1,2-dimethoxyethane; water; at 80 ℃; for 4h;
DOI:10.1039/c1ob05505d

Reference yield: 91.0%

: 201230-82-2
carbon monoxide

: 2-[2-(1-phenylethylidene)hydrazinyl]pyridine

: 536-74-3
phenylacetylene

: 16054-93-6
2-phenyl-4H-pyrido[1,2-a]pyrimidin-4-one

Guidance literature:: With dimanganese decacarbonyl; In toluene; at 100 ℃; for 16h; under 760.051 Torr; Reagent/catalyst; Catalytic behavior; Schlenk technique; Sealed tube;
DOI:10.1002/anie.201801111