1,3-Bis(acetoxymethyl)tetramethyldisiloxane

Base Information

• Chemical Name: 1,3-Bis(acetoxymethyl)tetramethyldisiloxane
• CAS No.: 5360-04-3
• Molecular Formula: C10H22 O5 Si2
• Molecular Weight: 278.453
• Hs Code.: 2934999090
• European Community (EC) Number: 226-345-9
• NSC Number: 96848
• UNII: KNH4TAD9GX
• DSSTox Substance ID: DTXSID10884151
• Nikkaji Number: J217.927J
• Wikidata: Q82862880
• Mol file: 5360-04-3.mol

Synonyms:1,3-Bis(acetoxymethyl)tetramethyldisiloxane;5360-04-3;KNH4TAD9GX;NSC-96848;Methanol, (1,1,3,3-tetramethyl-1,3-disiloxanediyl)bis-, diacetate;Methanol, 1,1'-(1,1,3,3-tetramethyl-1,3-disiloxanediyl)bis-, 1,1'-diacetate;(1,1,3,3-Tetramethyl-1,3-disiloxanediyl)dimethyl diacetate;3-Oxa-2,4-disilapentane-1,5-diol, 2,2,4,4-tetramethyl-, diacetate;NSC96848;UNII-KNH4TAD9GX;NCIOpen2_006393;SCHEMBL4941379;DTXSID10884151;[[acetyloxymethyl(dimethyl)silyl]oxy-dimethylsilyl]methyl acetate;EINECS 226-345-9;NSC 96848;3-Oxa-2,5-diol, 2,2,4,4-tetramethyl-, diacetate;25639-99-0

Chemical Property of 1,3-Bis(acetoxymethyl)tetramethyldisiloxane

Chemical Property:

• Vapor Pressure: 0.0505mmHg at 25°C
• Boiling Point: 235.3°Cat760mmHg
• Flash Point: 80°C
• PSA: 61.83000
• Density: 1g/cm³
• LogP: 2.45440
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 8
• Exact Mass: 278.10057687
• Heavy Atom Count: 17
• Complexity: 260

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)OC[Si](C)(C)O[Si](C)(C)COC(=O)C

Technology Process of 1,3-Bis(acetoxymethyl)tetramethyldisiloxane

There total 10 articles about 1,3-Bis(acetoxymethyl)tetramethyldisiloxane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

potassium acetate (127-08-2) + 1,3-Bis(chloromethyl)-1,1,3,3-tetramethyldisiloxane (2362-10-9) → (1,1,3,3-tetramethyldisiloxane-1,3-diyl)bis(methylene)diacetate (5360-04-3)

Guidance literature:

In N,N-dimethyl-formamide; for 6h; Reflux;

DOI:10.1515/mgmc-2012-0010

Reference yield: 75.0%

acetic acid (64-19-7,77671-22-8) + 1,3-Bis(chloromethyl)-1,1,3,3-tetramethyldisiloxane (2362-10-9) → (1,1,3,3-tetramethyldisiloxane-1,3-diyl)bis(methylene)diacetate (5360-04-3)

Guidance literature:

With triethylamine; In 5,5-dimethyl-1,3-cyclohexadiene; at 20 - 140 ℃; for 14h;

Reference yield:

1,3-Bis(chloromethyl)-1,1,3,3-tetramethyldisiloxane (2362-10-9) → (1,1,3,3-tetramethyldisiloxane-1,3-diyl)bis(methylene)diacetate (5360-04-3)

Guidance literature:

With KCH₃COO;

DOI:10.1021/ja01172a094

upstream raw materials:

1-chloromethylpentamethyldisiloxane

potassium acetate

acetic acid

1,3-Bis(chloromethyl)-1,1,3,3-tetramethyldisiloxane

Downstream raw materials:

acetic acid methyl ester

Hexamethylcyclotrisiloxane

(1,1,3,3-tetramethyldisiloxane-1,3-diyl)dimethanol

1,3-bis-(3,5-dinitro-benzoyloxymethyl)-1,1,3,3-tetramethyl-disiloxane