tris(2,4,6-tribromophenoxy)dichlorophosphorane

Base Information

• Chemical Name: tris(2,4,6-tribromophenoxy)dichlorophosphorane
• CAS No.: 112475-42-0
• Molecular Formula: C18H6 Br9 Cl2 O3 P
• Molecular Weight: 1091.25
• Mol file: 112475-42-0.mol

Synonyms:Tris(2,4,6-tribromophenoxy)dichlorophosphorane

Chemical Property of tris(2,4,6-tribromophenoxy)dichlorophosphorane

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 41.28000
• Density: g/cm³
• LogP: 13.69180

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of tris(2,4,6-tribromophenoxy)dichlorophosphorane

There total 2 articles about tris(2,4,6-tribromophenoxy)dichlorophosphorane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

2,4,6-tribromophenol (118-79-6) → tris(2,4,6-tribromo-phenoxy)dichlorophosphorane (112475-42-0)

Guidance literature:

With phosphorus pentachloride; In toluene; for 6h; Heating;

Reference yield:

tris(2,4,6-tribromophenyl)phosphite (7046-65-3) → tris(2,4,6-tribromophenyl)dichlorophosphorane + tris(2,4,6-tribromo-phenoxy)dichlorophosphorane (112475-42-0)

Guidance literature:

In chloroform;

Reference yield:

3,3'-O,N-dibenzoylthymidine (94189-81-8) + tris(2,4,6-tribromo-phenoxy)dichlorophosphorane (112475-42-0) + triethylammonium S-phenyl 5'-O-(4,4'-dimethoxytrityl)-3-N-benzoylthymidine 3'-phosphorothioate (94189-77-2) → (2,4,6-tribromophenyl)phosphate triester (7046-64-2) + C68H61N4O16PS (94189-82-9)

Guidance literature:

With pyridine; 3-nitro-1,2,4-triazole; Product distribution; multistep reaction;

DOI:10.1016/S0040-4039(00)95393-0

upstream raw materials:

2,4,6-tribromophenol

tris(2,4,6-tribromophenyl)phosphite

Downstream raw materials:

(2,4,6-tribromophenyl)phosphate triester

C₆₈H₆₁N₄O₁₆PS

Refernces

• 1、 -. "Method for the synthesis of nucleotide or oligonucleotide phosphoramidites". . . Retrieved 2008/06/13.