94189-82-9Relevant articles and documents
TRIS(2,4,6-TRIBROMOPHENOXY)DICHLOROPHOSPHORANE: A NOVEL CONDENSING AGENT FOR RAPID INTERNUCLEOTID BOND FORMATION IN THE PHOSPHOTRIESTER APPROACH
Hotoda, Hitoshi,Wada, Takeshi,Sekine, Mitsuo,Hata, Tsujiaki
, p. 1681 - 1684 (2007/10/02)
A new class of condensing agent, Tris(2,4,6-tribromophenoxy)-dichlorophosphorane (BDCP), was applied to the oligodeoxyribonucleotide synthesis.This reagent enabled us to perform a rapid internucleotidic bond formation in the phosphotriester approach only
A NEW CLASS OF CONDENSING REAGENTS FOR RAPID INTERNUCLEOTIDE BOND FORMATION IN THE PHOSPHOTRIESTER APPROACH AND PREPARATION OF N3-BENZOYLTHYMIDINE AS A KEY INTERMEDIATE IN OLIGODEOXYRIBONUCLEOTIDE SYNTHESIS
Matsuzaki, Jun-ichi,Hotoda, Hitoshi,Sekine, Mitsuo,Hata, Tujiaki
, p. 4019 - 4022 (2007/10/02)
Rapid internucleotide bond formation in the phosphotriester approach has been achieved in high yield by use of bis(2,4,6-trihalophenyl)phosphorochloridates (TCP and TBP) as new condensing reagents and the benzoyl group as the N3-imide protecting group of thymidine.