(2E)-1,1-Dimethyl-2-[(2E)-3-phenylprop-2-en-1-ylidene]hydrazine

Base Information

• Chemical Name: (2E)-1,1-Dimethyl-2-[(2E)-3-phenylprop-2-en-1-ylidene]hydrazine
• CAS No.: 13466-39-2
• Molecular Formula: C11H14N2
• Molecular Weight: 174.246
• NSC Number: 172907,220270
• DSSTox Substance ID: DTXSID10430637
• Mol file: 13466-39-2.mol

Synonyms:13466-39-2;NSC172907;SCHEMBL7815292;SCHEMBL7815295;DTXSID10430637;NSC220270;NSC-172907;NSC-220270;N-(cinnamylideneamino)-N-methylmethanamine;(2E)-1,1-Dimethyl-2-[(2E)-3-phenylprop-2-en-1-ylidene]hydrazine

Chemical Property of (2E)-1,1-Dimethyl-2-[(2E)-3-phenylprop-2-en-1-ylidene]hydrazine

Chemical Property:

• Vapor Pressure: 0.00576mmHg at 25°C
• Boiling Point: 273.4°Cat760mmHg
• Flash Point: 119.1°C
• Density: 0.89g/cm³
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 174.115698455
• Heavy Atom Count: 13
• Complexity: 177

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)N=CC=CC1=CC=CC=C1
• Isomeric SMILES: CN(C)/N=C/C=C/C1=CC=CC=C1

Technology Process of (2E)-1,1-Dimethyl-2-[(2E)-3-phenylprop-2-en-1-ylidene]hydrazine

There total 10 articles about (2E)-1,1-Dimethyl-2-[(2E)-3-phenylprop-2-en-1-ylidene]hydrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

N,N-Dimethylhydrazine (57-14-7) + 3-phenyl-propenal (104-55-2) → cinnamaldehyde N,N-dimethylhydrazone (13466-39-2)

Guidance literature:

With magnesium sulfate; In dichloromethane; at 20 ℃; for 10h;

DOI:10.1021/ol2016803

Reference yield: 82.0%

[(E)-2-(N',N'-Dimethyl-hydrazino)-vinyl]-triphenyl-phosphonium; bromide (128592-69-8) + benzaldehyde (100-52-7) → cinnamaldehyde N,N-dimethylhydrazone (13466-39-2)

Guidance literature:

With potassium tert-butylate; Mechanism; other aldehydes and ketones;

DOI:10.1016/S0040-4039(00)94550-7

Reference yield: 81.0%

2-(Dimethylamino)-3-phenylpropanal-dimethylhydrazon (101542-20-5) → cinnamaldehyde N,N-dimethylhydrazone (13466-39-2)

Guidance literature:

With methyl iodide; In toluene; for 1.5h; Heating;

upstream raw materials:

acetaldehydedimethylhydrazone

benzaldehyde

phenylacetic acid

glyoxal mono(dimethylhydrazone)

Downstream raw materials:

3-(N',N'-Dimethyl-hydrazino)-5-phenyl-cyclopentane-1,1,2,2-tetracarbonitrile

3-phenyl-propenal

D-205

cinnamonitrile